CENPT and PPCDC

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		CENPT	PPCDC
Description		centromere protein T	phosphopantothenoylcysteine decarboxylase
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body	Cytosol
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Heterodimerization Activity	Phosphopantothenoylcysteine Decarboxylase Activity Protein Binding Identical Protein Binding
	Biological Process	Mitotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Chromosome Segregation CENP-A Containing Nucleosome Assembly Chromosome Organization Cell Division Kinetochore Assembly	Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Coenzyme A biosynthesis
Drugs			Riboflavin Monophosphate Pantothenoylaminoethenethiol
Diseases
GWAS		Schizophrenia ( 25056061 29483656)	Adverse response to chemotherapy (amenorrhea) in breast cancer ( 31371054) Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707) Heel bone mineral density ( 30598549) Systemic lupus erythematosus ( 26502338)
Interacting Genes		9 interacting genes: APP CENPW COPS5 CYB5B DHX29 H3C1 PPCDC SNCB TCEA2	9 interacting genes: CENPT DBI FOXR1 NTAQ1 PPIG PSMA1 SREK1IP1 TXN2 ZNF232
Entrez ID		80152	60490
HPRD ID		07811	14377
Ensembl ID		ENSG00000102901	ENSG00000138621
Uniprot IDs		B3KPB2 Q96BT3	H3BQB0 H3BRQ0 H3BSE3 H3BU63 Q96CD2
PDB IDs			1QZU
Enriched GO Terms of Interacting Partners?
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