THOC7 and THOC5

Number of citations of the paper that reports this interaction (PubMedID 19059247)
8

Data Source:
HPRD (in vitro)

		THOC7	THOC5
Description		THO complex 7	THO complex 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding Protein Binding	MRNA Binding Protein Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Viral MRNA Export From Host Cell Nucleus	RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing Monocyte Differentiation MRNA 3'-end Processing Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Primitive Hemopoiesis Negative Regulation Of DNA Damage Checkpoint
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 28991256 25056061 29483656 30285260) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)	Carotid atherosclerosis in HIV infection ( 20009918) Lipid traits ( 24023261)
Interacting Genes		7 interacting genes: CHD3 CKAP4 GOT2 MED22 MED8 NIF3L1 THOC5	10 interacting genes: CSF1R CSNK2A1 HSPB1 LIG4 LSM3 NXF1 PPIL1 PRKCA THOC7 ZNF830
Entrez ID		80145	8563
HPRD ID		17632	16650
Ensembl ID		ENSG00000163634	ENSG00000100296
Uniprot IDs		A0A024R332 Q6I9Y2	A0A024R1D6 Q13769
PDB IDs
Enriched GO Terms of Interacting Partners?
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