THOC7 and MED22

Number of citations of the paper that reports this interaction (PubMedID 12584197)
20

Data Source:
BioGRID (pull down)

		THOC7	MED22
Description		THO complex 7	mediator complex subunit 22
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck	Cytoplasm Mediator Complex
	Molecular Function	RNA Binding Protein Binding	Transcription Coregulator Activity Protein Binding
	Biological Process	RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing MRNA 3'-end Processing Viral MRNA Export From Host Cell Nucleus	Regulation Of Transcription By RNA Polymerase II
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Schizophrenia ( 28991256 25056061 29483656 30285260) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)	Blood protein levels ( 28240269) Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		7 interacting genes: CHD3 CKAP4 GOT2 MED22 MED8 NIF3L1 THOC5	9 interacting genes: FBXO7 GOLM1 MED11 MED17 MED27 MED30 MED8 MED9 THOC7
Entrez ID		80145	6837
HPRD ID		17632	01713
Ensembl ID		ENSG00000163634	ENSG00000148297
Uniprot IDs		A0A024R332 Q6I9Y2	A0A024R8C5 Q15528
PDB IDs
Enriched GO Terms of Interacting Partners?
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