NLRX1 and PDZD3

		NLRX1	PDZD3
Description		NLR family member X1	PDZ domain containing 3
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Plasma Membrane Cell Junction	Cytosol Plasma Membrane Brush Border Apical Junction Complex Apical Part Of Cell
	Molecular Function	Protein Binding ATP Binding	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Ubiquitin-specific Protease Binding
	Biological Process	Viral Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Interferon-beta Production Negative Regulation Of Interleukin-6 Production Intracellular Signal Transduction Negative Regulation Of RIG-I Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Negative Regulation Of Innate Immune Response Negative Regulation Of Inflammatory Response	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta Negative regulators of DDX58/IFIH1 signaling	Intestinal infectious diseases
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: ABCG4 BUD13 C1QTNF5 IFT46 PDZD3 SARM1 SCN3B TMEM25 TMPRSS4	18 interacting genes: ABCC2 ASAP3 CACNA1S CFTR GUCY2C NLRX1 PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7
Entrez ID		79671	79849
HPRD ID		17640	06191
Ensembl ID		ENSG00000160703	ENSG00000172367
Uniprot IDs		Q86UT6	B0YJ61 Q86UT5
PDB IDs		3UN9	2V90
Enriched GO Terms of Interacting Partners?
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