RNF128 and OTUB1

Number of citations of the paper that reports this interaction (PubMedID 14661020)
58

Data Source:
BioGRID (pull down)

		RNF128	OTUB1
Description		ring finger protein 128	OTU deubiquitinase, ubiquitin aldehyde binding 1
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GO Annotations	Cellular Component	Late Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding NEDD8-specific Protease Activity Ubiquitin Protein Ligase Binding Ubiquitin Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Deubiquitination Regulation Of Protein Stability Negative Regulation Of Cytokine Biosynthetic Process Protein Localization To Lysosome Positive Regulation Of Protein Catabolic Process In The Vacuole	Adaptive Immune Response DNA Repair Cellular Response To DNA Damage Stimulus Protein Deubiquitination Protein K48-linked Deubiquitination Cellular Response To Interleukin-1 Negative Regulation Of Histone H2A K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair
Pathways		Ub-specific processing proteases Ovarian tumor domain proteases	Ub-specific processing proteases Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Creatinine levels ( 31015462) Estimated glomerular filtration rate ( 31015462)	Bipolar disorder ( 31043756)
Interacting Genes		14 interacting genes: APPBP2 CD151 CD40LG CD81 CEP76 OTUB1 TBK1 TP53 UBE2D1 UBE2E1 UBE2H UBE2I UBE2N UBE2T	51 interacting genes: ACVR1 ACVR1B ANXA1 ANXA7 AURKA BIRC2 BMPR1A BMPR1B CDKN1A CPEB2 CSNK2A1 ECT2 ESR1 FOXM1 H2AX IL1RL2 KDM1A MAPT NEDD8 PJA1 RFFL RHOA RNF126 RNF128 SLC7A11 SMAD2 SMAD3 SMAD4 SMAD9 SNAI1 TGFBR1 TP53 TRAF6 TRIM54 TRIM55 TRIM63 TSC22D1 TTR UBA6 UBC UBD UBE2D2 UBE2D4 UBE2N UBE2S UBE2V2 UBE2Z UBE4B USP15 USP21 USP28
Entrez ID		79589	55611
HPRD ID		02340	08493
Ensembl ID		ENSG00000133135	ENSG00000167770
Uniprot IDs		Q8TEB7	B3KUV5 Q96FW1
PDB IDs		3ICU	2ZFY 3VON 4DDG 4DDI 4DHZ 4I6L 4LDT
Enriched GO Terms of Interacting Partners?
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