OTUB1

Description		OTU deubiquitinase, ubiquitin aldehyde binding 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding NEDD8-specific Protease Activity Ubiquitin Protein Ligase Binding Ubiquitin Binding
	Biological Process	Adaptive Immune Response DNA Repair Cellular Response To DNA Damage Stimulus Protein Deubiquitination Protein K48-linked Deubiquitination Cellular Response To Interleukin-1 Negative Regulation Of Histone H2A K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair
Pathways		Ub-specific processing proteases Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)
Interacting Genes		51 interacting genes: ACVR1 ACVR1B ANXA1 ANXA7 AURKA BIRC2 BMPR1A BMPR1B CDKN1A CPEB2 CSNK2A1 ECT2 ESR1 FOXM1 H2AX IL1RL2 KDM1A MAPT NEDD8 PJA1 RFFL RHOA RNF126 RNF128 SLC7A11 SMAD2 SMAD3 SMAD4 SMAD9 SNAI1 TGFBR1 TP53 TRAF6 TRIM54 TRIM55 TRIM63 TSC22D1 TTR UBA6 UBC UBD UBE2D2 UBE2D4 UBE2N UBE2S UBE2V2 UBE2Z UBE4B USP15 USP21 USP28
Entrez ID		55611
HPRD ID		08493
Ensembl ID		ENSG00000167770
Uniprot IDs		B3KUV5 Q96FW1
PDB IDs		2ZFY 3VON 4DDG 4DDI 4DHZ 4I6L 4LDT
Enriched GO Terms of Interacting Partners?
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