NKAP and PRPF3

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		NKAP	PRPF3
Description		NFKB activating protein	pre-mRNA processing factor 3
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome
	Molecular Function	Chromatin Binding RNA Binding Protein Binding Chromatin DNA Binding	RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Stem Cell Population Maintenance Granulocyte Differentiation T Cell Differentiation In Thymus Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Alpha-beta T Cell Differentiation Hematopoietic Stem Cell Proliferation	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS			Blood protein levels ( 28240269) Chronotype ( 27494321) Low density lipoprotein cholesterol levels ( 30498476) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Platelet count ( 27863252) Plateletcrit ( 27863252)
Interacting Genes		17 interacting genes: CEP70 DHX15 DHX8 FAM124A FRA10AC1 LUC7L2 PCBP2 PPIG PRPF3 PRPF40A RBM39 RBMX2 SRPK1 SRPK2 THAP1 TTC14 U2AF1	31 interacting genes: BRCA1 CASK CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GPRASP2 GTPBP3 MAPRE1 MID2 NAV2 NKAP PCBP1 PHC2 PRPF31 PSMD3 RBM39 SART3 SNIP1 SNRNP200 TRIM39 U2AF2 USP4 WBP4 ZBTB8A ZCCHC10 ZGPAT
Entrez ID		79576	9129
HPRD ID		06666	07389
Ensembl ID		ENSG00000101882	ENSG00000117360
Uniprot IDs		Q8N5F7	O43395
PDB IDs		6QDV	1X4Q 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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