PRPF3 and SART3

Number of citations of the paper that reports this interaction (PubMedID 12374753)
67

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PRPF3	SART3
Description		pre-mRNA processing factor 3	spliceosome associated factor 3, U4/U6 recycling protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Nucleus Nucleoplasm U6atac SnRNP Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex ASAP Complex U4/U6 SnRNP U4atac/U6atac SnRNP
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	RNA Binding Protein Binding U6 SnRNA Binding U4 SnRNA Binding U6atac SnRNA Binding Histone Binding Ubiquitin-specific Protease Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Spliceosomal Tri-snRNP Complex Assembly Regulation Of Alternative MRNA Splicing, Via Spliceosome Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Cell Morphogenesis Nucleosome Assembly RNA Splicing Regulation Of Gene Expression Homeostasis Of Number Of Cells Hematopoietic Stem Cell Proliferation Positive Regulation Of Histone Deubiquitination
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases		Retinitis pigmentosa (RP)	Disseminated superficial actinic porokeratosis (DSAP)
GWAS		Blood protein levels ( 28240269) Chronotype ( 27494321) Low density lipoprotein cholesterol levels ( 30498476) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Platelet count ( 27863252) Plateletcrit ( 27863252)	Acne (severe) ( 24927181)
Interacting Genes		31 interacting genes: BRCA1 CASK CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GPRASP2 GTPBP3 MAPRE1 MID2 NAV2 NKAP PCBP1 PHC2 PRPF31 PSMD3 RBM39 SART3 SNIP1 SNRNP200 TRIM39 U2AF2 USP4 WBP4 ZBTB8A ZCCHC10 ZGPAT	10 interacting genes: AR C6 COIL H2AC20 H2BC21 KPNA2 LSM7 MEGF10 PRPF3 RNPS1
Entrez ID		9129	9733
HPRD ID		07389	11532
Ensembl ID		ENSG00000117360	ENSG00000075856
Uniprot IDs		O43395	A0A499FI31 Q15020
PDB IDs		1X4Q 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	2DO4 5CTQ 5CTR 5CTT 5JJW 5JJX 5JPZ
Enriched GO Terms of Interacting Partners?
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