C11orf49 and ARHGEF15

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

		C11orf49	ARHGEF15
Description		chromosome 11 open reading frame 49	Rho guanine nucleotide exchange factor 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Dendrite
	Molecular Function	Protein Binding	Rho Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding
	Biological Process		Positive Regulation Of GTPase Activity Regulation Of Catalytic Activity Positive Regulation Of Stress Fiber Assembly Retina Vasculature Morphogenesis In Camera-type Eye Negative Regulation Of Synapse Maturation
Pathways			NRAGE signals death through JNK Rho GTPase cycle G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) D-dimer levels ( 21502573) Intraocular pressure ( 29617998) Neurociticism ( 29500382)	Bipolar disorder ( 28115744) LDL cholesterol ( 30275531) Total cholesterol levels ( 30275531)
Interacting Genes		12 interacting genes: ARHGEF15 CDC16 GSR PNMA5 PSMA1 RAB17 RAB29 RBM48 RPL8 RPS3A UBE3A UBQLN4	9 interacting genes: C11orf49 CEP55 DNAJC5 EPHA4 ESR1 ESRRG LASP1 MOB4 PIN1
Entrez ID		79096	22899
HPRD ID		08332	10535
Ensembl ID		ENSG00000149179	ENSG00000198844
Uniprot IDs		B4DUV7 Q9H6J7	A0A0S2Z547 O94989
PDB IDs
Enriched GO Terms of Interacting Partners?
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