ZNF177 and ARHGAP21

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZNF177	ARHGAP21
Description		zinc finger protein 177	Rho GTPase activating protein 21
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Blood Microparticle	Golgi Membrane Cell Golgi Apparatus Cytosol Plasma Membrane Actin Cytoskeleton Cell Junction Cytoplasmic Vesicle Membrane
	Molecular Function	DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding	GTPase Activator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Golgi Organization Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Golgi Localization Establishment Of Golgi Localization Maintenance Of Golgi Location Organelle Transport Along Microtubule
Pathways			Rho GTPase cycle
Drugs
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Birth weight ( 31043758) Diisocyanate-induced asthma ( 25918132) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Optic disc area ( 31798171) Optic disc size ( 31809533) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		3 interacting genes: ARHGAP21 RHOU SLC37A3	6 interacting genes: ARF1 EEF1D PTK2B RHOA SP1 ZNF177
Entrez ID		7730	57584
HPRD ID		03175	06445
Ensembl ID		ENSG00000188629	ENSG00000107863
Uniprot IDs		Q13360	Q5T5U3
PDB IDs			2DHJ 2J59 2YUY
Enriched GO Terms of Interacting Partners?
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