ARHGAP21 and ZNF177

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ARHGAP21	ZNF177
Description		Rho GTPase activating protein 21	zinc finger protein 177
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cell Golgi Apparatus Cytosol Plasma Membrane Actin Cytoskeleton Cell Junction Cytoplasmic Vesicle Membrane	Nucleus Blood Microparticle
	Molecular Function	GTPase Activator Activity Protein Binding	DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Golgi Organization Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Golgi Localization Establishment Of Golgi Localization Maintenance Of Golgi Location Organelle Transport Along Microtubule	Negative Regulation Of Transcription By RNA Polymerase II
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Birth weight ( 31043758) Diisocyanate-induced asthma ( 25918132) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Optic disc area ( 31798171) Optic disc size ( 31809533) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		6 interacting genes: ARF1 EEF1D PTK2B RHOA SP1 ZNF177	3 interacting genes: ARHGAP21 RHOU SLC37A3
Entrez ID		57584	7730
HPRD ID		06445	03175
Ensembl ID		ENSG00000107863	ENSG00000188629
Uniprot IDs		Q5T5U3	Q13360
PDB IDs		2DHJ 2J59 2YUY
Enriched GO Terms of Interacting Partners?
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