CA12 and CUX1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		CA12	CUX1
Description		carbonic anhydrase 12	cut like homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Golgi Membrane Nucleus Nucleoplasm Golgi Apparatus Cytosol
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Protein Binding, Bridging Sequence-specific DNA Binding
	Biological Process	Bicarbonate Transport Chloride Ion Homeostasis	Negative Regulation Of Transcription By RNA Polymerase II Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Golgi Vesicle Transport Positive Regulation Of Dendrite Morphogenesis
Pathways		Reversible hydration of carbon dioxide	Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic
Drugs		Benzthiazide Hydroflumethiazide Acetazolamide Zonisamide Hydrochlorothiazide Ellagic Acid
Diseases
GWAS		Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)	Attention deficit hyperactivity disorder symptom score ( 27663945) Basal cell carcinoma ( 31174203 27539887) Breast cancer ( 29059683) Cerebellum cortex volume ( 31530798) Chronotype ( 30696823) Intelligence (MTAG) ( 29326435) Keratinocyte cancer (MTAG) ( 31174203) Mean platelet volume ( 27863252) Morning person ( 30696823) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Response to antidepressants ( 22584459) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		10 interacting genes: ATP5F1C CUX1 DAXX KATNBL1 LGALS7 MAPK6 MRPL9 RDH11 SGSM2 TOE1	21 interacting genes: BIN1 CA12 CCNA1 CDC25A CDK1 CDK7 CREBBP CTSL CYTH2 EHMT2 ELAC2 GOLGA5 HMGB1 KAT2B MAX RB1 RECQL5 SATB1 SDC3 SUMO2 TLE4
Entrez ID		771	1523
HPRD ID		04464	00295
Ensembl ID		ENSG00000074410	ENSG00000257923
Uniprot IDs		B3KUB4 O43570	P39880 Q13948 Q3LIA3
PDB IDs		1JCZ 1JD0 4HT2 4KP5 4KP8 4Q0L 4QJ0 4QJO 4QJW 4WW8 5LL5 5LL9 5LLO 5LLP 5MSA 5MSB 6G5L 6G7A 6RPS
Enriched GO Terms of Interacting Partners?
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