CUX1 and CA12

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		CUX1	CA12
Description		cut like homeobox 1	carbonic anhydrase 12
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Golgi Apparatus Cytosol	Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Protein Binding, Bridging Sequence-specific DNA Binding	Carbonate Dehydratase Activity Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Retrograde Transport, Vesicle Recycling Within Golgi Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Golgi Vesicle Transport Positive Regulation Of Dendrite Morphogenesis	Bicarbonate Transport Chloride Ion Homeostasis
Pathways		Signaling by cytosolic FGFR1 fusion mutants Signaling by FGFR1 in disease Intra-Golgi traffic	Reversible hydration of carbon dioxide
Drugs			Benzthiazide Hydroflumethiazide Acetazolamide Zonisamide Hydrochlorothiazide Ellagic Acid
Diseases
GWAS		Attention deficit hyperactivity disorder symptom score ( 27663945) Basal cell carcinoma ( 31174203 27539887) Breast cancer ( 29059683) Cerebellum cortex volume ( 31530798) Chronotype ( 30696823) Intelligence (MTAG) ( 29326435) Keratinocyte cancer (MTAG) ( 31174203) Mean platelet volume ( 27863252) Morning person ( 30696823) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Response to antidepressants ( 22584459) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808)
Interacting Genes		21 interacting genes: BIN1 CA12 CCNA1 CDC25A CDK1 CDK7 CREBBP CTSL CYTH2 EHMT2 ELAC2 GOLGA5 HMGB1 KAT2B MAX RB1 RECQL5 SATB1 SDC3 SUMO2 TLE4	10 interacting genes: ATP5F1C CUX1 DAXX KATNBL1 LGALS7 MAPK6 MRPL9 RDH11 SGSM2 TOE1
Entrez ID		1523	771
HPRD ID		00295	04464
Ensembl ID		ENSG00000257923	ENSG00000074410
Uniprot IDs		P39880 Q13948 Q3LIA3	B3KUB4 O43570
PDB IDs			1JCZ 1JD0 4HT2 4KP5 4KP8 4Q0L 4QJ0 4QJO 4QJW 4WW8 5LL5 5LL9 5LLO 5LLP 5MSA 5MSB 6G5L 6G7A 6RPS
Enriched GO Terms of Interacting Partners?
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