PCGF2 and ABHD6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PCGF2	ABHD6
Description		polycomb group ring finger 2	abhydrolase domain containing 6, acylglycerol lipase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex	Mitochondrion Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Mitochondrial Membrane AMPA Glutamate Receptor Complex Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Membrane
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Promoter-specific Chromatin Binding	Phospholipase Activity Acylglycerol Lipase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Chromatin Silencing Anterior/posterior Pattern Specification Histone Acetylation Histone H2A-K119 Monoubiquitination Embryonic Skeletal System Morphogenesis Cellular Response To Hydrogen Peroxide Negative Regulation Of G0 To G1 Transition Negative Regulation Of Apoptotic Signaling Pathway	Phospholipid Catabolic Process Negative Regulation Of Cell Migration Acylglycerol Catabolic Process Positive Regulation Of Lipid Biosynthetic Process Monoacylglycerol Catabolic Process Long-term Synaptic Depression Negative Regulation Of Cold-induced Thermogenesis Regulation Of Endocannabinoid Signaling Pathway Lysobisphosphatidic Acid Metabolic Process
Pathways		SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins Activation of anterior HOX genes in hindbrain development during early embryogenesis Transcriptional Regulation by E2F6	Arachidonate production from DAG
Drugs
Diseases
GWAS			Platelet count ( 27863252) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 27399966 26502338)
Interacting Genes		21 interacting genes: ABHD6 CBX2 CBX6 CCND2 CD247 CTNNAL1 GJB5 HOXC9 HSF2 LMNA PHC2 RBCK1 RNF2 SPDEF UBE2D3 UBE2E2 UBE2Q2 UBE2T UBE2U USP11 USP7	2 interacting genes: CKMT2 PCGF2
Entrez ID		7703	57406
HPRD ID		10621	12407
Ensembl ID		ENSG00000277258	ENSG00000163686
Uniprot IDs		A0A024R1V6 P35227	A0A024R323 Q9BV23
PDB IDs
Enriched GO Terms of Interacting Partners?
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