ABHD6 and PCGF2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ABHD6	PCGF2
Description		abhydrolase domain containing 6, acylglycerol lipase	polycomb group ring finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Late Endosome Membrane Mitochondrial Membrane AMPA Glutamate Receptor Complex Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Membrane	Nuclear Chromatin Sex Chromatin Nucleus Nucleoplasm Nuclear Body PcG Protein Complex PRC1 Complex
	Molecular Function	Phospholipase Activity Acylglycerol Lipase Activity	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding Promoter-specific Chromatin Binding
	Biological Process	Phospholipid Catabolic Process Negative Regulation Of Cell Migration Acylglycerol Catabolic Process Positive Regulation Of Lipid Biosynthetic Process Monoacylglycerol Catabolic Process Long-term Synaptic Depression Negative Regulation Of Cold-induced Thermogenesis Regulation Of Endocannabinoid Signaling Pathway Lysobisphosphatidic Acid Metabolic Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Chromatin Silencing Anterior/posterior Pattern Specification Histone Acetylation Histone H2A-K119 Monoubiquitination Embryonic Skeletal System Morphogenesis Cellular Response To Hydrogen Peroxide Negative Regulation Of G0 To G1 Transition Negative Regulation Of Apoptotic Signaling Pathway
Pathways		Arachidonate production from DAG	SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins Activation of anterior HOX genes in hindbrain development during early embryogenesis Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Platelet count ( 27863252) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 27399966 26502338)
Interacting Genes		2 interacting genes: CKMT2 PCGF2	21 interacting genes: ABHD6 CBX2 CBX6 CCND2 CD247 CTNNAL1 GJB5 HOXC9 HSF2 LMNA PHC2 RBCK1 RNF2 SPDEF UBE2D3 UBE2E2 UBE2Q2 UBE2T UBE2U USP11 USP7
Entrez ID		57406	7703
HPRD ID		12407	10621
Ensembl ID		ENSG00000163686	ENSG00000277258
Uniprot IDs		A0A024R323 Q9BV23	A0A024R1V6 P35227
PDB IDs
Enriched GO Terms of Interacting Partners?
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