VDAC1 and KLHL40

Number of citations of the paper that reports this interaction (PubMedID 24960163)
34

Data Source:
BioGRID (two hybrid)

		VDAC1	KLHL40
Description		voltage dependent anion channel 1	kelch like family member 40
Image
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Synaptic Vesicle Membrane Mitochondrial Nucleoid Membrane Raft Pore Complex Extracellular Exosome	Cytoplasm Cul3-RING Ubiquitin Ligase Complex A Band I Band
	Molecular Function	Protein Binding Voltage-gated Anion Channel Activity Porin Activity Protein Kinase Binding Identical Protein Binding Ion Channel Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Behavioral Fear Response Pyruvate Metabolic Process Anion Transport Mitochondrial Calcium Ion Transmembrane Transport Apoptotic Process Neuron-neuron Synaptic Transmission Learning Inorganic Anion Transport Viral Process Macroautophagy Epithelial Cell Differentiation Anion Transmembrane Transport Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Reactive Oxygen Species Metabolic Process	Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Skeletal Muscle Fiber Development Skeletal Muscle Fiber Differentiation
Pathways		Mitochondrial protein import Pink/Parkin Mediated Mitophagy Ub-specific processing proteases Pyruvate metabolism Mitochondrial calcium ion transport
Drugs		Aluminium monostearate
Diseases
GWAS		Alopecia areata ( 25608926) Metabolite levels ( 23823483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		22 interacting genes: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PPIF PRKCE PRKN RAF1 RNF31 SUMO4 TOMM20 TUBA4A	9 interacting genes: AHNAK C7orf31 CC2D1B LMOD3 LRRC29 REL TASOR2 VDAC1 ZBED1
Entrez ID		7416	131377
HPRD ID		05137	11058
Ensembl ID		ENSG00000213585	ENSG00000157119
Uniprot IDs		A0A1L1UHR1 B3KTS5 P21796	A8K5H9 Q2TBA0
PDB IDs		2JK4 2K4T 5JDP 5XDN 5XDO 6G6U 6G73	4ASC
Enriched GO Terms of Interacting Partners?
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