KLHL40 and VDAC1

Number of citations of the paper that reports this interaction (PubMedID 24960163)
34

Data Source:
BioGRID (two hybrid)

		KLHL40	VDAC1
Description		kelch like family member 40	voltage dependent anion channel 1
Image
GO Annotations	Cellular Component	Cytoplasm Cul3-RING Ubiquitin Ligase Complex A Band I Band	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Synaptic Vesicle Membrane Mitochondrial Nucleoid Membrane Raft Pore Complex Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Voltage-gated Anion Channel Activity Porin Activity Protein Kinase Binding Identical Protein Binding Ion Channel Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Skeletal Muscle Fiber Development Skeletal Muscle Fiber Differentiation	Behavioral Fear Response Pyruvate Metabolic Process Anion Transport Mitochondrial Calcium Ion Transmembrane Transport Apoptotic Process Neuron-neuron Synaptic Transmission Learning Inorganic Anion Transport Viral Process Macroautophagy Epithelial Cell Differentiation Anion Transmembrane Transport Regulation Of Autophagy Of Mitochondrion Negative Regulation Of Reactive Oxygen Species Metabolic Process
Pathways			Mitochondrial protein import Pink/Parkin Mediated Mitophagy Ub-specific processing proteases Pyruvate metabolism Mitochondrial calcium ion transport
Drugs			Aluminium monostearate
Diseases
GWAS			Alopecia areata ( 25608926) Metabolite levels ( 23823483) Systemic lupus erythematosus ( 28714469) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		9 interacting genes: AHNAK C7orf31 CC2D1B LMOD3 LRRC29 REL TASOR2 VDAC1 ZBED1	22 interacting genes: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PPIF PRKCE PRKN RAF1 RNF31 SUMO4 TOMM20 TUBA4A
Entrez ID		131377	7416
HPRD ID		11058	05137
Ensembl ID		ENSG00000157119	ENSG00000213585
Uniprot IDs		A8K5H9 Q2TBA0	A0A1L1UHR1 B3KTS5 P21796
PDB IDs		4ASC	2JK4 2K4T 5JDP 5XDN 5XDO 6G6U 6G73
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?