Description |
tumor protein p53 |
aurora kinase A |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Phosphonothreonine
- AT9283
- CYC116
- Alisertib
- 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE
- 8-ethyl-3,10,10-trimethyl-4,5,6,8,10,12-hexahydropyrazolo[4',3':6,7]cyclohepta[1,2-b]pyrrolo[2,3-f]indol-9(1H)-one
- 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}-3-[3-(trifluoromethyl)phenyl]urea
- 1-(3-chlorophenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-1,3-thiazol-2-yl}urea
- 1-(5-{2-[(1-methyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino]ethyl}-1,3-thiazol-2-yl)-3-[3-(trifluoromethyl)phenyl]urea
- N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE
- N-butyl-3-{[6-(9H-purin-6-ylamino)hexanoyl]amino}benzamide
- 2-(1H-pyrazol-3-yl)-1H-benzimidazole
- N-[3-(1H-BENZIMIDAZOL-2-YL)-1H-PYRAZOL-4-YL]BENZAMIDE
- MLN8054
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Diseases |
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GWAS |
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Interacting Genes |
482 interacting genes:
ABL1
ACKR3
ACTA1
AGT
AIMP2
AKT1
ANK2
ANKRD2
ANTKMT
ANXA2
ANXA3
APBB2
APEX1
APOH
APPL1
APTX
ARAF
ARID1A
ARID3A
ARIH2
ARL3
ARNT
ASH2L
ATF3
ATM
ATR
ATRX
ATXN3
AURKA
AXIN1
BAG5
BAIAP2L1
BAK1
BANP
BARD1
BAX
BCCIP
BCL2
BCL2L1
BCL2L12
BCL2L2
BCL6
BCR
BLM
BMP1
BRCA1
BRCA2
BRD7
BRF1
BTBD2
BTK
C10orf90
CABLES1
CABLES2
CAPG
CAPN1
CARM1
CBLC
CCDC106
CCL18
CCNA2
CCNG1
CCNH
CCT5
CD40LG
CDC14A
CDC14B
CDC25C
CDC42
CDK1
CDK2
CDK4
CDK5
CDK6
CDK7
CDK8
CDK9
CDKN1A
CDKN2A
CDKN2B
CDKN2C
CEBPZ
CENPX
CETP
CHD3
CHEK1
CHEK2
CHUK
COP1
COPS2
COPS3
COPS4
COPS5
COPS6
COPS7A
COPS8
COX17
CR2
CRBN
CREBBP
CREBZF
CRK
CSNK1A1
CSNK1D
CSNK2A1
CSNK2A2
CSNK2B
CUL9
CXXC1
CYLD
DAPK3
DAXX
DCAF1
DDX20
DDX5
DGKZ
DHCR24
DHFR
DLEU1
DMTF1
DNAJB1
DNAJC7
DNMT3L
DTL
DVL2
E2F1
E4F1
EAF2
EEF2
EFEMP2
EGLN3
EGR1
EHMT1
EHMT2
EIF2AK2
EIF2S2
ELL
ELL3
EP300
EPHA2
EPHA3
ERBB2
ERCC2
ERCC3
ERCC6
ERH
ESR1
FBXO11
FBXO42
FCAMR
FGFR4
FOXO3
FXYD6
FZR1
GADD45A
GNL3
GPS1
GPS2
GPX2
GSK3B
GSTM4
GTF2H1
GTF2H4
GYS2
HABP4
HDAC1
HDAC2
HDAC3
HECTD3
HECW1
HEY1
HIF1A
HINFP
HIPK1
HIPK2
HMGA2
HMGB1
HMGB2
HNF4A
HNRNPUL1
HSP90AA1
HSP90AB1
HSP90B1
HSPA1A
HSPA8
HSPA9
HSPB1
HTT
HUWE1
IFI16
IKBKB
ING1
ING4
ING5
IRF7
ITPK1
KAT2A
KAT2B
KAT5
KAT6A
KAT7
KAT8
KDM1A
KDM4D
KIAA0087
KLF4
KLF6
KMT5A
KPNA2
KPNA4
KPNB1
LACTB
LAMA4
LAMTOR5
LATS2
LDB3
MAD2L1BP
MAGEA2
MAGEB18
MAML1
MAP2K3
MAP2K5
MAP3K1
MAPK1
MAPK10
MAPK14
MAPK3
MAPK8
MAPK9
MAPKAPK5
MDC1
MDH1
MDM2
MDM4
MED1
MED17
MED21
MEN1
MET
MIF
MNAT1
MNDA
MPHOSPH6
MSL2
MSX1
MTA1
MTA2
MUC1
MUL1
MVP
MYBBP1A
MYC
NABP1
NABP2
NAP1L1
NAT10
NCL
NCOA1
NCOA2
NCOA3
NDN
NEDD8
NEIL3
NF2
NFKBIA
NFYA
NFYB
NGFR
NMT1
NMT2
NOP53
NPM1
NQO1
NR0B2
NR3C1
NR4A1
NTHL1
OTUB1
OTUD5
PADI1
PAFAH1B3
PARP1
PBK
PCDHA4
PDGFRA
PDLIM7
PELI1
PELI2
PELP1
PER2
PHB
PIAS1
PIAS2
PIAS4
PIN1
PLAGL1
PLCG2
PLK1
PLK3
PML
PNP
POLA1
PPA1
PPARGC1A
PPIB
PPM1D
PPP1CA
PPP1CC
PPP1R13L
PPP2CA
PPP2R2B
PPP4C
PRIM1
PRKAB2
PRKCA
PRKD1
PRKDC
PRKN
PRKRA
PRMT1
PSMB3
PSMC5
PSMD11
PSMD4
PSME3
PTEN
PTGS2
PTK2
PTTG1
RAB4A
RAB7A
RAD51
RANBP9
RAP1B
RB1
RBBP6
RBCK1
RBPJ
RCC1
RCHY1
RELA
RING1
RNF125
RNF128
RNF38
RPA1
RPS3
RPS6KA1
RPS6KA2
RPS6KA3
RRM2
RRM2B
RUNX3
S100A2
S100A4
S100A6
S100A8
S100B
SAT1
SCAMP1
SERPINB9
SETD7
SFN
SHISA5
SIN3A
SIN3B
SIRT1
SLC9A9
SMAD2
SMAD3
SMARCA4
SMARCB1
SMARCD1
SMN1
SMYD2
SNRPN
SP1
SP3
SRC
SRSF1
SSTR3
STAMBP
STARD10
STAT6
STK11
STK4
STX5
SUB1
SULT1E1
SUMO1
SYVN1
TADA3
TAF1
TAF1A
TAF1B
TAF1C
TAF9
TAF9B
TBP
TCF4
TEAD2
TEC
TEP1
TFAP2A
TFAP2C
TFDP1
TFIP11
THAP12
THAP8
THRB
TIAF1
TK1
TOP1
TOP1MT
TOP2A
TOP2B
TOPORS
TP53BP1
TP53BP2
TP53INP1
TP53RK
TP63
TP73
TRIAP1
TRIM27
TRIM39
TSC22D1
TSG101
TTK
TWIST1
TXN
UBB
UBE2A
UBE2D1
UBE2I
UBE2K
UBE2L3
UBE2M
UBE2N
UBE2Q1
UBE2V2
UBE3A
UFD1
UHRF1
UHRF2
UIMC1
USP11
USP21
USP24
USP28
USP3
USP42
USP49
USP7
UTP14A
VRK1
WDR33
WDR5
WDR82
WRN
WT1
WWOX
XAF1
XPO1
XRCC6
YBX1
YWHAG
YWHAZ
YY1
YY2
ZBTB2
ZBTB49
ZCCHC10
ZHX1
ZIC3
ZMIZ2
ZNF148
ZNF24
ZNF302
ZNF679
ZNF839
ZNHIT1
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141 interacting genes:
AATF
AKT1
ANGPTL4
APP
ARPC1B
ARPC2
ATRX
AURKAIP1
BCL2L1
BEX2
BIRC5
BLID
BORA
BRAF
BRCA1
BTK
CBX3
CCND2
CCNE1
CDC20
CDC25B
CDH13
CHFR
CKAP5
CSN2
CTCFL
DACH1
DKK3
EHMT2
EPHA2
EPSTI1
ERBB2
ERRFI1
FANCA
FOXF1
FOXP1
FZR1
GADD45A
GMNN
GSK3B
GTF3C4
H3-4
HDAC2
HDAC6
HIF1A
HNRNPF
HNRNPK
IFI16
IKBKB
INCENP
KIF11
KIF2C
KLHL18
KLK5
LATS2
LYPD3
MAP2K3
MAP3K5
MAPRE2
MAPRE3
MBD3
MDM2
MED26
MTA3
MYC
MYT1
MYT1L
NAT2
NDC80
NEDD9
NF2
NFKBIA
NFXL1
NIN
NKX1-1
NME1
NSD2
NUF2
OTUB1
OTUD7B
PARP10
PAX4
PDGFRA
PDLIM2
PLK3
PML
POU4F3
PPP1CA
PPP1CB
PPP1CC
PRKACA
PSEN2
PSMC3IP
PTPRD
PTTG1
PUM2
RASSF1
RELA
REST
S100A14
SCGB3A1
SIN3B
SOX18
SOX3
SOX30
SOX4
SREBF2
SRPK1
SRPK2
SSRP1
STAT2
STK11
SUPT20H
SWT1
TACC1
TACC3
TBX10
TCEAL2
TCERG1
TCF3
TEAD2
TFAP2B
THRSP
TLK1
TLK2
TP53
TP73
TPX2
TRRAP
TSC1
UBE2C
UBE2I
UBE2N
UBTF
USP2
USP21
VHL
WIF1
YY1
ZFHX3
ZKSCAN2
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Entrez ID |
7157 |
6790 |
HPRD ID |
01859 |
04066 |
Ensembl ID |
ENSG00000141510
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ENSG00000087586
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Uniprot IDs |
A0A087WT22
A0A087WXZ1
A0A087X1Q1
H2EHT1
K7PPA8
P04637
Q53GA5
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O14965
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PDB IDs |
1A1U
1AIE
1C26
1DT7
1GZH
1H26
1HS5
1JSP
1KZY
1MA3
1OLG
1OLH
1PES
1PET
1SAE
1SAF
1SAK
1SAL
1TSR
1TUP
1UOL
1XQH
1YC5
1YCQ
1YCR
1YCS
2AC0
2ADY
2AHI
2ATA
2B3G
2BIM
2BIN
2BIO
2BIP
2BIQ
2F1X
2FEJ
2FOJ
2FOO
2GS0
2H1L
2H2D
2H2F
2H4F
2H4H
2H4J
2H59
2J0Z
2J10
2J11
2J1W
2J1X
2J1Y
2J1Z
2J20
2J21
2K8F
2L14
2LY4
2MEJ
2MWO
2MWP
2MWY
2MZD
2OCJ
2PCX
2RUK
2VUK
2WGX
2X0U
2X0V
2X0W
2XWR
2YBG
2YDR
2Z5S
2Z5T
3D05
3D06
3D07
3D08
3D09
3D0A
3DAB
3DAC
3IGK
3IGL
3KMD
3KZ8
3LW1
3OQ5
3PDH
3Q01
3Q05
3Q06
3SAK
3TG5
3TS8
3ZME
4AGL
4AGM
4AGN
4AGO
4AGP
4AGQ
4BUZ
4BV2
4HFZ
4HJE
4IBQ
4IBS
4IBT
4IBU
4IBV
4IBW
4IBY
4IBZ
4IJT
4KVP
4LO9
4LOE
4LOF
4MZI
4MZR
4QO1
4RP6
4RP7
4X34
4XR8
4ZZJ
5A7B
5AB9
5ABA
5AOI
5AOJ
5AOK
5AOL
5AOM
5BUA
5ECG
5G4M
5G4N
5G4O
5HOU
5HP0
5HPD
5LAP
5LGY
5MCT
5MCU
5MCV
5MCW
5MF7
5MG7
5MHC
5MOC
5O1A
5O1B
5O1C
5O1D
5O1E
5O1F
5O1G
5O1H
5O1I
5OL0
5UN8
5XZC
6FF9
6FJ5
6GGA
6GGB
6GGC
6GGD
6GGE
6GGF
6RZ3
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1MQ4
1MUO
1OL5
1OL6
1OL7
2BMC
2C6D
2C6E
2DWB
2J4Z
2J50
2NP8
2W1C
2W1D
2W1E
2W1F
2W1G
2WQE
2WTV
2WTW
2X6D
2X6E
2X81
2XNE
2XNG
2XRU
3COH
3E5A
3EFW
3FDN
3H0Y
3H0Z
3H10
3HA6
3K5U
3LAU
3M11
3MYG
3NRM
3O50
3O51
3P9J
3QBN
3R21
3R22
3UNZ
3UO4
3UO5
3UO6
3UOD
3UOH
3UOJ
3UOK
3UOL
3UP2
3UP7
3VAP
3W10
3W16
3W18
3W2C
4B0G
4BN1
4BYI
4BYJ
4C3P
4C3R
4CEG
4DEA
4DEB
4DED
4DEE
4DHF
4J8M
4J8N
4JAI
4JAJ
4JBO
4JBP
4JBQ
4O0S
4O0U
4O0W
4PRJ
4UYN
4UZD
4UZH
4ZS0
4ZTQ
4ZTR
4ZTS
5AAD
5AAE
5AAF
5AAG
5DN3
5DNR
5DOS
5DPV
5DR2
5DR6
5DR9
5DRD
5DT0
5DT3
5DT4
5EW9
5G15
5G1X
5L8J
5L8K
5L8L
5LXM
5OBJ
5OBR
5ODT
5ONE
5ORL
5ORN
5ORO
5ORP
5ORR
5ORS
5ORT
5ORV
5ORW
5ORX
5ORY
5ORZ
5OS0
5OS1
5OS2
5OS3
5OS4
5OS5
5OS6
5OSD
5OSE
5OSF
5ZAN
6C2R
6C2T
6C83
6CPE
6CPF
6CPG
6GRA
6HJJ
6HJK
6I2U
6R49
6R4A
6R4B
6R4C
6R4D
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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