Description |
tumor protein p53 |
mitogen-activated protein kinase 14 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- Dasatinib
- 4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine
- N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea
- 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One
- Inhibitor of P38 Kinase
- 6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine
- 3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine
- 1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea
- 3-(Benzyloxy)Pyridin-2-Amine
- 1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One
- 4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline
- 1-(5-Tert-Butyl-2-P-Tolyl-2h-Pyrazol-3-Yl)-3-[4-(2-Morpholin-4-Yl-Ethoxy)-Naphthalen-1-Yl]-Urea
- 2-Chlorophenol
- 4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole
- SB220025
- 4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE
- Triazolopyridine
- KC706
- Talmapimod
- VX-702
- 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea
- N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide
- N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide
- Neflamapimod
- N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide
- 4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE
- 4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE
- N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide
- 4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE
- 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde
- N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide
- N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide
- N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide
- PH-797804
- 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
- 2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol
- N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA
- N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-
- 3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE
- 3-fluoro-N-1H-indol-5-yl-5-morpholin-4-ylbenzamide
- 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE
- 3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA
- 8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM
- 2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE
- N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide
- N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
- N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide
- 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine
- 2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE
- [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE
- [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE
- 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE
- 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE
- 3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE
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Diseases |
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GWAS |
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- Foot ulcer in diabetes and neuropathy ( 28672053)
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Interacting Genes |
482 interacting genes:
ABL1
ACKR3
ACTA1
AGT
AIMP2
AKT1
ANK2
ANKRD2
ANTKMT
ANXA2
ANXA3
APBB2
APEX1
APOH
APPL1
APTX
ARAF
ARID1A
ARID3A
ARIH2
ARL3
ARNT
ASH2L
ATF3
ATM
ATR
ATRX
ATXN3
AURKA
AXIN1
BAG5
BAIAP2L1
BAK1
BANP
BARD1
BAX
BCCIP
BCL2
BCL2L1
BCL2L12
BCL2L2
BCL6
BCR
BLM
BMP1
BRCA1
BRCA2
BRD7
BRF1
BTBD2
BTK
C10orf90
CABLES1
CABLES2
CAPG
CAPN1
CARM1
CBLC
CCDC106
CCL18
CCNA2
CCNG1
CCNH
CCT5
CD40LG
CDC14A
CDC14B
CDC25C
CDC42
CDK1
CDK2
CDK4
CDK5
CDK6
CDK7
CDK8
CDK9
CDKN1A
CDKN2A
CDKN2B
CDKN2C
CEBPZ
CENPX
CETP
CHD3
CHEK1
CHEK2
CHUK
COP1
COPS2
COPS3
COPS4
COPS5
COPS6
COPS7A
COPS8
COX17
CR2
CRBN
CREBBP
CREBZF
CRK
CSNK1A1
CSNK1D
CSNK2A1
CSNK2A2
CSNK2B
CUL9
CXXC1
CYLD
DAPK3
DAXX
DCAF1
DDX20
DDX5
DGKZ
DHCR24
DHFR
DLEU1
DMTF1
DNAJB1
DNAJC7
DNMT3L
DTL
DVL2
E2F1
E4F1
EAF2
EEF2
EFEMP2
EGLN3
EGR1
EHMT1
EHMT2
EIF2AK2
EIF2S2
ELL
ELL3
EP300
EPHA2
EPHA3
ERBB2
ERCC2
ERCC3
ERCC6
ERH
ESR1
FBXO11
FBXO42
FCAMR
FGFR4
FOXO3
FXYD6
FZR1
GADD45A
GNL3
GPS1
GPS2
GPX2
GSK3B
GSTM4
GTF2H1
GTF2H4
GYS2
HABP4
HDAC1
HDAC2
HDAC3
HECTD3
HECW1
HEY1
HIF1A
HINFP
HIPK1
HIPK2
HMGA2
HMGB1
HMGB2
HNF4A
HNRNPUL1
HSP90AA1
HSP90AB1
HSP90B1
HSPA1A
HSPA8
HSPA9
HSPB1
HTT
HUWE1
IFI16
IKBKB
ING1
ING4
ING5
IRF7
ITPK1
KAT2A
KAT2B
KAT5
KAT6A
KAT7
KAT8
KDM1A
KDM4D
KIAA0087
KLF4
KLF6
KMT5A
KPNA2
KPNA4
KPNB1
LACTB
LAMA4
LAMTOR5
LATS2
LDB3
MAD2L1BP
MAGEA2
MAGEB18
MAML1
MAP2K3
MAP2K5
MAP3K1
MAPK1
MAPK10
MAPK14
MAPK3
MAPK8
MAPK9
MAPKAPK5
MDC1
MDH1
MDM2
MDM4
MED1
MED17
MED21
MEN1
MET
MIF
MNAT1
MNDA
MPHOSPH6
MSL2
MSX1
MTA1
MTA2
MUC1
MUL1
MVP
MYBBP1A
MYC
NABP1
NABP2
NAP1L1
NAT10
NCL
NCOA1
NCOA2
NCOA3
NDN
NEDD8
NEIL3
NF2
NFKBIA
NFYA
NFYB
NGFR
NMT1
NMT2
NOP53
NPM1
NQO1
NR0B2
NR3C1
NR4A1
NTHL1
OTUB1
OTUD5
PADI1
PAFAH1B3
PARP1
PBK
PCDHA4
PDGFRA
PDLIM7
PELI1
PELI2
PELP1
PER2
PHB
PIAS1
PIAS2
PIAS4
PIN1
PLAGL1
PLCG2
PLK1
PLK3
PML
PNP
POLA1
PPA1
PPARGC1A
PPIB
PPM1D
PPP1CA
PPP1CC
PPP1R13L
PPP2CA
PPP2R2B
PPP4C
PRIM1
PRKAB2
PRKCA
PRKD1
PRKDC
PRKN
PRKRA
PRMT1
PSMB3
PSMC5
PSMD11
PSMD4
PSME3
PTEN
PTGS2
PTK2
PTTG1
RAB4A
RAB7A
RAD51
RANBP9
RAP1B
RB1
RBBP6
RBCK1
RBPJ
RCC1
RCHY1
RELA
RING1
RNF125
RNF128
RNF38
RPA1
RPS3
RPS6KA1
RPS6KA2
RPS6KA3
RRM2
RRM2B
RUNX3
S100A2
S100A4
S100A6
S100A8
S100B
SAT1
SCAMP1
SERPINB9
SETD7
SFN
SHISA5
SIN3A
SIN3B
SIRT1
SLC9A9
SMAD2
SMAD3
SMARCA4
SMARCB1
SMARCD1
SMN1
SMYD2
SNRPN
SP1
SP3
SRC
SRSF1
SSTR3
STAMBP
STARD10
STAT6
STK11
STK4
STX5
SUB1
SULT1E1
SUMO1
SYVN1
TADA3
TAF1
TAF1A
TAF1B
TAF1C
TAF9
TAF9B
TBP
TCF4
TEAD2
TEC
TEP1
TFAP2A
TFAP2C
TFDP1
TFIP11
THAP12
THAP8
THRB
TIAF1
TK1
TOP1
TOP1MT
TOP2A
TOP2B
TOPORS
TP53BP1
TP53BP2
TP53INP1
TP53RK
TP63
TP73
TRIAP1
TRIM27
TRIM39
TSC22D1
TSG101
TTK
TWIST1
TXN
UBB
UBE2A
UBE2D1
UBE2I
UBE2K
UBE2L3
UBE2M
UBE2N
UBE2Q1
UBE2V2
UBE3A
UFD1
UHRF1
UHRF2
UIMC1
USP11
USP21
USP24
USP28
USP3
USP42
USP49
USP7
UTP14A
VRK1
WDR33
WDR5
WDR82
WRN
WT1
WWOX
XAF1
XPO1
XRCC6
YBX1
YWHAG
YWHAZ
YY1
YY2
ZBTB2
ZBTB49
ZCCHC10
ZHX1
ZIC3
ZMIZ2
ZNF148
ZNF24
ZNF302
ZNF679
ZNF839
ZNHIT1
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164 interacting genes:
AIMP1
AKT1
ARNT
ATF2
BCL2
BCL2L1
BICD1
BMI1
CCDC14
CCDC97
CCND2
CD4
CDC25A
CDC25B
CDC25C
CDK4
CDK6
CDKN2A
CDT1
CDX2
CENPC
CEP164
COPS5
CREB1
CSNK2A1
CSNK2A2
CSNK2B
DAB1
DDIT3
DUSP1
DUSP10
DUSP16
DUSP2
DUSP22
DUSP4
DUSP7
DUSP9
DYRK1B
EEA1
EEF1A1
EEF2K
EGFR
EIF4EBP1
ELK1
ELK3
EPB42
EPHA2
EPS15
ESR1
ETV1
FGFR4
FKBP8
FLNA
GADD45A
GATA3
GDF15
GMFB
GORASP2
GRB2
HDAC3
HIVEP1
HNF4A
HSF4
HSPB1
HTRA2
ILKAP
INTS6L
IRAK1
JDP2
JUN
JUNB
KAT2A
KAT2B
KMT2C
KRT18
KRT8
LATS2
LIMK1
MAFA
MAP2K1
MAP2K3
MAP2K4
MAP2K6
MAP2K7
MAP3K10
MAP3K7
MAPK1
MAPK3
MAPK8
MAPKAPK2
MAPKAPK3
MAPKAPK5
MAPT
MARS1
MAX
MBP
MEF2A
MEF2C
MEF2D
MIDEAS
MITF
MKNK1
MKNK2
MOB3B
MUC12
MYC
NCOA3
NF2
NFATC1
NFATC4
NFIC
NKTR
NRL
NUP153
PAK6
PHC2
PI4K2B
PLA2G4A
PLG
PML
PPARGC1A
PPP4R3A
PTPN7
RBSN
RELA
RET
ROBO1
RPL22
RPL41
RPS6KA4
RPS6KA5
S100A9
SCN8A
SH2D1A
SHC1
SLC9A1
SMAD3
SMAD7
SMARCD3
SNAPIN
SPAG9
SPTBN1
SQSTM1
SRPK1
SRSF5
STAT1
STAT4
STK11
STK39
SUPT20H
TAB1
TCF20
TFCP2
TLE5
TMEM63B
TP53
TRAF6
TSC1
UGT2B10
ULK1
YY1AP1
ZFP36L1
ZNF142
ZNHIT1
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Entrez ID |
7157 |
1432 |
HPRD ID |
01859 |
02619 |
Ensembl ID |
ENSG00000141510
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ENSG00000112062
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Uniprot IDs |
A0A087WT22
A0A087WXZ1
A0A087X1Q1
H2EHT1
K7PPA8
P04637
Q53GA5
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A0A024RD15
B4E0K5
L7RSM2
Q16539
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PDB IDs |
1A1U
1AIE
1C26
1DT7
1GZH
1H26
1HS5
1JSP
1KZY
1MA3
1OLG
1OLH
1PES
1PET
1SAE
1SAF
1SAK
1SAL
1TSR
1TUP
1UOL
1XQH
1YC5
1YCQ
1YCR
1YCS
2AC0
2ADY
2AHI
2ATA
2B3G
2BIM
2BIN
2BIO
2BIP
2BIQ
2F1X
2FEJ
2FOJ
2FOO
2GS0
2H1L
2H2D
2H2F
2H4F
2H4H
2H4J
2H59
2J0Z
2J10
2J11
2J1W
2J1X
2J1Y
2J1Z
2J20
2J21
2K8F
2L14
2LY4
2MEJ
2MWO
2MWP
2MWY
2MZD
2OCJ
2PCX
2RUK
2VUK
2WGX
2X0U
2X0V
2X0W
2XWR
2YBG
2YDR
2Z5S
2Z5T
3D05
3D06
3D07
3D08
3D09
3D0A
3DAB
3DAC
3IGK
3IGL
3KMD
3KZ8
3LW1
3OQ5
3PDH
3Q01
3Q05
3Q06
3SAK
3TG5
3TS8
3ZME
4AGL
4AGM
4AGN
4AGO
4AGP
4AGQ
4BUZ
4BV2
4HFZ
4HJE
4IBQ
4IBS
4IBT
4IBU
4IBV
4IBW
4IBY
4IBZ
4IJT
4KVP
4LO9
4LOE
4LOF
4MZI
4MZR
4QO1
4RP6
4RP7
4X34
4XR8
4ZZJ
5A7B
5AB9
5ABA
5AOI
5AOJ
5AOK
5AOL
5AOM
5BUA
5ECG
5G4M
5G4N
5G4O
5HOU
5HP0
5HPD
5LAP
5LGY
5MCT
5MCU
5MCV
5MCW
5MF7
5MG7
5MHC
5MOC
5O1A
5O1B
5O1C
5O1D
5O1E
5O1F
5O1G
5O1H
5O1I
5OL0
5UN8
5XZC
6FF9
6FJ5
6GGA
6GGB
6GGC
6GGD
6GGE
6GGF
6RZ3
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1A9U
1BL6
1BL7
1BMK
1DI9
1IAN
1KV1
1KV2
1M7Q
1OUK
1OUY
1OVE
1OZ1
1R39
1R3C
1W7H
1W82
1W83
1W84
1WBN
1WBO
1WBS
1WBT
1WBV
1WBW
1WFC
1YQJ
1ZYJ
1ZZ2
1ZZL
2BAJ
2BAK
2BAL
2BAQ
2FSL
2FSM
2FSO
2FST
2GFS
2I0H
2LGC
2NPQ
2OKR
2ONL
2QD9
2RG5
2RG6
2Y8O
2YIS
2YIW
2YIX
2ZAZ
2ZB0
2ZB1
3BV2
3BV3
3BX5
3C5U
3CTQ
3D7Z
3D83
3DS6
3DT1
3E92
3E93
3FC1
3FI4
3FKL
3FKN
3FKO
3FL4
3FLN
3FLQ
3FLS
3FLW
3FLY
3FLZ
3FMH
3FMJ
3FMK
3FML
3FMM
3FMN
3FSF
3FSK
3GC7
3GCP
3GCQ
3GCS
3GCU
3GCV
3GFE
3GI3
3HA8
3HEC
3HEG
3HL7
3HLL
3HP2
3HP5
3HRB
3HUB
3HUC
3HV3
3HV4
3HV5
3HV6
3HV7
3HVC
3IPH
3ITZ
3IW5
3IW6
3IW7
3IW8
3K3I
3K3J
3KF7
3KQ7
3L8S
3L8X
3LFA
3LFB
3LFC
3LFD
3LFE
3LFF
3LHJ
3MGY
3MH0
3MH1
3MH2
3MH3
3MPA
3MPT
3MVL
3MVM
3MW1
3NEW
3NNU
3NNV
3NNW
3NNX
3NWW
3O8P
3O8T
3O8U
3OBG
3OBJ
3OC1
3OCG
3OD6
3ODY
3ODZ
3OEF
3PG3
3QUD
3QUE
3RIN
3ROC
3S3I
3S4Q
3U8W
3UVP
3UVQ
3UVR
3ZS5
3ZSG
3ZSH
3ZSI
3ZYA
4A9Y
4AA0
4AA4
4AA5
4AAC
4DLI
4DLJ
4E5A
4E5B
4E6A
4E6C
4E8A
4EH2
4EH3
4EH4
4EH5
4EH6
4EH7
4EH8
4EH9
4EHV
4EWQ
4F9W
4F9Y
4FA2
4GEO
4KIN
4KIP
4KIQ
4L8M
4R3C
4ZTH
5ETA
5ETC
5ETF
5ETI
5ML5
5MTX
5MTY
5MZ3
5N63
5N64
5N65
5N66
5N67
5N68
5O8U
5O8V
5OMG
5OMH
5TBE
5TCO
5WJJ
5XYX
5XYY
6ANL
6HWT
6HWU
6HWV
6M95
6M9L
6OHD
6SFI
6SFJ
6SFK
6SFO
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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