TNS1 and KLF10

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		TNS1	KLF10
Description		tensin 1	Kruppel like factor 10
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Focal Adhesion Cell Surface	Nuclear Chromatin Nucleus
	Molecular Function	RNA Binding Actin Binding Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Cell-substrate Junction Assembly Fibroblast Migration	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Circadian Rhythm Negative Regulation Of Cell Proliferation Cellular Response To Starvation Bone Mineralization Somatic Stem Cell Population Maintenance Regulation Of Circadian Rhythm Positive Regulation Of Osteoclast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Peptide
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Asthma and hay fever ( 24388013) Chronic obstructive pulmonary disease ( 30804561) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Diastolic blood pressure ( 28135244 27841878) Diverticular disease ( 30177863) FEV1 ( 30804560) Height ( 21998595 28552196 20881960 25282103 25429064) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Intraocular pressure ( 29617998 29785010 30054594 29235454) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 28166213 30804560) Lung function (FVC) ( 28166213 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Mitral valve prolapse ( 26301497) Pulmonary function ( 20010834) Pulmonary function (smoking interaction) ( 23284291) Systolic blood pressure ( 27841878 30578418)	Chronic lymphocytic leukemia ( 23770605) IgA nephropathy ( 26028593) Neurofibrillary tangles ( 31497858) Urate levels ( 31578528)
Interacting Genes		7 interacting genes: CAPN2 FRS3 KLF10 OSGEP PPP1CC PTK2 YWHAZ	16 interacting genes: BOP1 CDK2 CDK6 CRIP2 FBXW7 KAT2B LENG1 PIGC RPL14 SF3B3 SIAH1 SIN3A SNHG29 SP1 TNS1 ZNF512B
Entrez ID		7145	7071
HPRD ID		02512	03527
Ensembl ID		ENSG00000079308	ENSG00000155090
Uniprot IDs		A1L0S7 B2RU35 B7Z6H8 E9PF55 E9PGF5 Q0VG54 Q0VG55 Q59G71 Q86VB0 Q9HBL0	Q13118
PDB IDs			2EPA
Enriched GO Terms of Interacting Partners?
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