TLE1 and MSX2

  • Number of citations of the paper that reports this interaction (PubMedID 20211142)
  • 329
  • Data Source:
  • BioGRID (two hybrid)

TLE1

MSX2

Description TLE family member 1, transcriptional corepressor msh homeobox 2
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Blond vs. brown/black hair color ( 30531825)
  • Chin dimples ( 27182965)
  • Chronotype ( 30696823)
  • Depressive symptoms (SSRI exposure interaction) ( 25649181)
  • Metabolite levels ( 23823483)
  • Night sleep phenotypes ( 27126917)
  • Red vs. brown/black hair color ( 30531825)
  • Resistant hypertension ( 30237584)
  • Stroke ( 26089329)
Interacting Genes 88 interacting genes: ANXA7 APH1A ARL3 ARL4D ATN1 BARHL1 BCL2L1 BID BTBD2 CCL18 CDK1 CDKN1A CDKN2C CELF3 CRCT1 CSNK2B CTNNB1 DAZAP2 DLEU1 DNAH5 EIF2S2 EN1 ERH ESRRG FOXA1 FOXA2 FOXA3 FOXG1 FUBP1 FXYD6 GADD45A GKAP1 GOLM1 GRB7 GSK3B GSTM4 HES1 HES6 HESX1 HHEX HLA-DQA1 HMGB1 HNF1A HSPE1 IL6ST KDM6A KIAA0408 KIF27 LEF1 MORF4L2 MPHOSPH6 MSX1 MSX2 NKX2-5 NUDT21 PAFAH1B3 PAX9 PCDHA4 PEX2 PFN1 POLB POLE2 PRDM1 PSMD11 RAP1B RCC1 RNF10 RPA2 RUNX1 RUNX3 SAT1 SERPINB9 SIX1 SIX2 SIX3 SIX6 SMN1 SNRPG TCF3 TCF4 TK1 TLE2 TLX1 TLX2 TLX3 TSC22D1 UTY ZFP64 23 interacting genes: ATXN1 CEBPA DLX2 DLX5 GTF2F1 GTF2F2 MAGED1 MAT2B MSX1 NR3C1 PIAS2 POLR3D POU2AF1 PPARG RUNX2 SPEN TLE1 TLE2 USP54 XRCC5 XRCC6 ZBTB17 ZDHHC2
Entrez ID 7088 4488
HPRD ID 02557 00421
Ensembl ID ENSG00000196781 ENSG00000120149
Uniprot IDs B4DEF9 Q04724 Q59EF7 P35548
PDB IDs 1GXR 2CE8 2CE9 4OM2 4OM3 5MWJ
Enriched GO Terms of Interacting Partners?
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