TEAD4 and CTBP1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		TEAD4	CTBP1
Description		TEA domain transcription factor 4	C-terminal binding protein 1
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex	Nucleus Nucleoplasm Transcriptional Repressor Complex Presynaptic Active Zone Cytoplasmic Component Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Protein C-terminus Binding Transcription Factor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Protein Domain Specific Binding Identical Protein Binding NAD Binding Repressing Transcription Factor Binding
	Biological Process	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Muscle Organ Development Hippo Signaling Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Silencing Protein Phosphorylation Negative Regulation Of Cell Proliferation Viral Genome Replication Positive Regulation Of Histone Deacetylation Negative Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated White Fat Cell Differentiation Regulation Of Cell Cycle Oxidation-reduction Process Negative Regulation Of Histone H4 Acetylation
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription	Deactivation of the beta-catenin transactivating complex SUMOylation of transcription cofactors Repression of WNT target genes TCF7L2 mutants don't bind CTBP
Drugs			Formic Acid
Diseases
GWAS		Narcolepsy with cataplexy ( 23496005)	Type 2 diabetes ( 31118516)
Interacting Genes		29 interacting genes: CCDC172 CCDC85B CCNDBP1 CEP55 CEP70 CTBP1 EXOC3-AS1 FBXO7 GOLGA2 HOMEZ KIAA0753 KRT40 KRTAP10-3 LZTS2 MDFI MTUS2 MYH7 PDE4DIP PFKM PNMA1 RABGEF1 RUNDC3A SSX2IP TRAF1 TRIM27 VGLL1 VPS52 WWTR1 YAP1	92 interacting genes: ACTL6B AKAP9 APC ARNT2 ATXN1L BCAS3 BCL3 BMPR2 BRCA1 CBX4 CDC23 CDKN2D CEP68 CHD3 CREBBP CRY2 CTBP2 CTNNA1 DGCR6 DMRTB1 EEF1D ELAC2 ELK3 EP300 FANCC FANCF FANCG FANCL FOXP1 FOXP2 FUNDC1 GTF2B H3-4 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC9 HEMGN HIC1 HOXB5 HTT IKZF1 IKZF2 KAT2B KDM1A KLF12 KLF3 LCORL LNX1 MAML2 MAPK9 MARCHF10 MECOM NME2 NOL4 NOL4L NOS1 NRIP1 NTAQ1 ORC4 PIAS2 PLCB1 PNN PRKAA1 PRKCI RAI2 RB1 RBBP5 RBBP8 RBM14 RCOR1 RNF111 SIN3A SNRPN SOBP SPEN TBP TCF4 TEAD4 TERF2 TERF2IP TGIF1 THAP11 TSHZ3 ZBP1 ZBTB18 ZEB1 ZEB2 ZFPM2 ZNF219
Entrez ID		7004	1487
HPRD ID		03421	04015
Ensembl ID		ENSG00000197905	ENSG00000159692
Uniprot IDs		Q15561	Q13363 X5D8Y5
PDB IDs		5GZB 5NO6 5OAQ 6GE3 6GE4 6GE5 6GE6 6GEC 6GEE 6GEG 6GEI 6GEK 6HIK 6Q2X 6Q36 6SEN 6SEO	1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR
Enriched GO Terms of Interacting Partners?
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