TAF10 and FTL

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TAF10	FTL
Description		TATA-box binding protein associated factor 10	ferritin light chain
Image
GO Annotations	Cellular Component	PCAF Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm STAGA Complex Transcription Factor TFTC Complex Perinuclear Region Of Cytoplasm	Extracellular Region Cell Cytoplasm Cytosol Intracellular Ferritin Complex Membrane Azurophil Granule Lumen Autolysosome Extracellular Exosome
	Molecular Function	DNA Binding Histone Acetyltransferase Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Enzyme Binding Estrogen Receptor Binding Identical Protein Binding RNA Polymerase Binding Promoter-specific Chromatin Binding	Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Identical Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Apoptotic Process Regulation Of Gene Expression Histone Deubiquitination Protein Deubiquitination Cellular Protein-containing Complex Assembly Multicellular Organism Growth Histone H3 Acetylation Regulation Of DNA Binding Hepatocyte Differentiation Regulation Of Signal Transduction By P53 Class Mediator	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Neutrophil Degranulation Iron Ion Homeostasis
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones Ub-specific processing proteases RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport
Drugs			Iron Dextran Protoporphyrin Sodium ferric gluconate complex
Diseases			Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia
GWAS
Interacting Genes		23 interacting genes: ATXN7 ESR1 FANCA FTL H3-4 POLR2A PSMC5 SETD7 SUPT7L TAF1 TAF11 TAF12 TAF13 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	26 interacting genes: CLEC4G FTH1 GADD45A GLP1R GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MPHOSPH6 MPP6 MTNR1B MYOC MYOG PIK3CA PPP1CC PTN RAP2A SDCBP SMAD9 SPINK7 TAF10 USHBP1 VKORC1 ZDHHC17
Entrez ID		6881	2512
HPRD ID		15972	00616
Ensembl ID		ENSG00000166337	ENSG00000087086
Uniprot IDs		Q12962	A0A384MDR3 P02792
PDB IDs		2F69 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 4J7F 4J7I 4J83 4J8O 4WV4 5EG2 6MZC 6MZD 6MZL 6MZM	2FFX 2FG4 2FG8 3KXU 4V6B 5LG8
Enriched GO Terms of Interacting Partners?
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