FTL and KPNA3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FTL	KPNA3
Description		ferritin light chain	karyopherin subunit alpha 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Cytoplasm Cytosol Intracellular Ferritin Complex Membrane Azurophil Granule Lumen Autolysosome Extracellular Exosome	Nuclear Pore Nucleoplasm Cytosol Host Cell
	Molecular Function	Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Identical Protein Binding	Protein Binding Protein C-terminus Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Neutrophil Degranulation Iron Ion Homeostasis	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process Viral Entry Into Host Cell Protein-containing Complex Assembly Viral Penetration Into Host Nucleus
Pathways		Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport	ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs		Iron Dextran Protoporphyrin Sodium ferric gluconate complex
Diseases		Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia
GWAS			Inflammatory skin disease ( 25574825) Menopause (age at onset) ( 22267201) Obesity-related traits ( 23251661) Triiodothyronine/thyroxine ratio ( 30824882)
Interacting Genes		26 interacting genes: CLEC4G FTH1 GADD45A GLP1R GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MPHOSPH6 MPP6 MTNR1B MYOC MYOG PIK3CA PPP1CC PTN RAP2A SDCBP SMAD9 SPINK7 TAF10 USHBP1 VKORC1 ZDHHC17	33 interacting genes: APOL6 ARNT CDKN1B COIL DDX21 EPAS1 EPHA2 ERCC3 FAM50B FTL GATA6 GTF2H1 GTF2IRD1 HIF1A HNRNPC HSPB1 KPNB1 MAT2B MVP MYOD1 NFE2L2 NFKB1 NUP50 RBBP4 RCC1 RPRD1A SLC5A11 TEX37 TGM2 TSSC4 ZBTB24 ZCCHC10 ZNF131
Entrez ID		2512	3839
HPRD ID		00616	03536
Ensembl ID		ENSG00000087086	ENSG00000102753
Uniprot IDs		A0A384MDR3 P02792	A0A024RDV7 O00505
PDB IDs		2FFX 2FG4 2FG8 3KXU 4V6B 5LG8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?