TADA2A and ARNT2

Number of citations of the paper that reports this interaction (PubMedID 24722188)
51

Data Source:
BioGRID (two hybrid)

		TADA2A	ARNT2
Description		transcriptional adaptor 2A	aryl hydrocarbon receptor nuclear translocator 2
Image			No pdb structure
GO Annotations	Cellular Component	PCAF Complex Nucleus Chromosome SAGA-type Complex	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Aryl Hydrocarbon Receptor Binding Protein-containing Complex Binding Protein Heterodimerization Activity
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Nucleic Acid-templated Transcription	Response To Hypoxia In Utero Embryonic Development Regulation Of Transcription, DNA-templated Xenobiotic Metabolic Process Central Nervous System Development Brain Development Positive Regulation Of Cell Proliferation Response To Estradiol Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		HATs acetylate histones	PPARA activates gene expression Phase I - Functionalization of compounds Endogenous sterols Xenobiotics Aryl hydrocarbon receptor signalling
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)	Atrial fibrillation ( 30061737 29892015) Attention deficit hyperactivity disorder ( 29325848) Bipolar disorder ( 20351715) Body mass index ( 26426971) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		39 interacting genes: ARNT2 C1orf109 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 MAGOH MCPH1 MFAP1 MTX2 MYC NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 TTC23 TTC9C ZFYVE26 ZNF564 ZNF688	62 interacting genes: ADAMTSL4 AHR APP ARNT CALCOCO2 CCDC33 CDR2 CEP57L1 CEP63 CTBP1 DGCR6 DTX2 DYDC1 EPAS1 GOLGA2 HIF1A IKZF3 KIFC3 LZTS2 MAGEA4 MAGED1 MEIS2 MEOX2 MIPOL1 MTDH MTUS2 NCOA3 NDE1 NPAS2 NPAS3 NPAS4 PDE4DIP PLSCR1 RBCK1 REL RFX6 RIMBP3 RINT1 SH3GL2 SIM1 SIM2 SORBS3 SPAG5 SSBP3 SSX2IP SYCE1 TACC3 TADA2A TAX1BP3 TFIP11 TRAF1 TRAF2 TRIM23 TRIM27 TRIM37 TRIM42 TRIP6 TSPOAP1 USHBP1 USP7 VPS52 ZNF341
Entrez ID		6871	9915
HPRD ID		03784	06915
Ensembl ID		ENSG00000276234	ENSG00000172379
Uniprot IDs		A0A024R0Y4 A0A087WWR4 B3KU13 O75478	Q7Z3A3 Q86TN1 Q9HBZ2 X5DQN9
PDB IDs		1X41
Enriched GO Terms of Interacting Partners?
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