TADA2A and PPP1R16B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TADA2A	PPP1R16B
Description		transcriptional adaptor 2A	protein phosphatase 1 regulatory subunit 16B
Image			No pdb structure
GO Annotations	Cellular Component	PCAF Complex Nucleus Chromosome SAGA-type Complex	Nucleus Plasma Membrane Nuclear Speck Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Chromatin Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding	Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Acetylation Histone H3 Acetylation Positive Regulation Of Nucleic Acid-templated Transcription	Positive Regulation Of Endothelial Cell Proliferation Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Protein Dephosphorylation Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Filopodium Assembly Establishment Of Endothelial Barrier Negative Regulation Of Peptidyl-serine Dephosphorylation Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Ovarian cancer ( 23535730)	Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis ( 28714907) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diverticular disease ( 30177863) Huntington's disease progression ( 28642124) Schizophrenia ( 25056061 29483656 30285260)
Interacting Genes		39 interacting genes: ARNT2 C1orf109 CCDC134 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FANCG FARS2 FBF1 GPSM3 HGS HNRNPLL KAT2A KLC4 KLHL38 KPNA2 MAGOH MCPH1 MFAP1 MTX2 MYC NOL4L-DT NR3C1 PPP1R16B PRKAB2 PRPF31 RNF6 RTL8B SF3A3 TADA3 TCF3 TEKT4 TTC23 TTC9C ZFYVE26 ZNF564 ZNF688	19 interacting genes: CDCA7L CEP55 CEP70 CRX DVL2 GATA1 GOLGA2 IKZF3 KCTD9 NEFL PHC2 PPP1CB RBPMS SF3B4 TADA2A TASOR2 TFIP11 TLE5 ZNF410
Entrez ID		6871	26051
HPRD ID		03784	15168
Ensembl ID		ENSG00000276234	ENSG00000101445
Uniprot IDs		A0A024R0Y4 A0A087WWR4 B3KU13 O75478	Q96T49
PDB IDs		1X41
Enriched GO Terms of Interacting Partners?
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