SSX5 and NFE2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		SSX5	NFE2
Description		SSX family member 5	nuclear factor, erythroid 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm PML Body Protein-DNA Complex
	Molecular Function	Nucleic Acid Binding Protein Binding	Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Sequence-specific DNA Binding Protein N-terminus Binding WW Domain Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Nucleosome Disassembly Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Blood Coagulation Hemostasis Blood Circulation Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated
Pathways			RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Chronotype ( 30696823) Mean platelet volume ( 22139419 24026423) Platelet count ( 29403010 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: AGTRAP NFE2 PCBD2 ZSCAN1	22 interacting genes: ATF4 BTRC CREBBP ELF5 HMGN1 ITCH KAT2B MAFF MAFG MAFK MAPK8 NEDD4 NFE2L2 NFE2L3 PEX14 PHYHIP PRIM1 SCAND1 SSX5 TXN WWP1 YAP1
Entrez ID		6758	4778
HPRD ID		02267	09030
Ensembl ID		ENSG00000165583	ENSG00000123405
Uniprot IDs		O60225	A8K3E0 Q16621
PDB IDs			1LVX 2KZ5
Enriched GO Terms of Interacting Partners?
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