SRP54 and KLK12

		SRP54	KLK12
Description		signal recognition particle 54	kallikrein related peptidase 12
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Nuclear Speck	Extracellular Region Extracellular Space Secretory Granule
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding Drug Binding 7S RNA Binding GDP Binding Endoplasmic Reticulum Signal Peptide Binding Ribonucleoprotein Complex Binding	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Response To Drug Protein Targeting To ER	Proteolysis Cornification
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	Formation of the cornified envelope
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Immunoglobulin light chain (AL) amyloidosis ( 28025584)	Blood protein levels ( 29875488 28240269)
Interacting Genes		8 interacting genes: EGLN3 KLK12 PRORP RALGAPA1 RNPS1 SRP19 STAB1 TKTL1	1 interacting genes: SRP54
Entrez ID		6729	43849
HPRD ID		05330	05705
Ensembl ID		ENSG00000100883	ENSG00000186474
Uniprot IDs		P61011	A0A024R4M4 B9EGA9 Q9UKR0
PDB IDs		1MFQ 1QB2 5L3Q
Enriched GO Terms of Interacting Partners?
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