SRMS and SKAP2

Number of citations of the paper that reports this interaction (PubMedID 29568343)
1

Data Source:
BioGRID (protein complementation assay)

		SRMS	SKAP2
Description		src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	src kinase associated phosphoprotein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signaling Receptor Binding Protein Binding ATP Binding	SH3/SH2 Adaptor Activity Protein Binding
	Biological Process	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Signal Transduction Cell Migration Peptidyl-tyrosine Phosphorylation Cell Differentiation Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation	Signal Transduction Negative Regulation Of Cell Proliferation Positive Regulation Of Signal Transduction B Cell Activation Protein-containing Complex Assembly
Pathways		PTK6 Down-Regulation	Signal regulatory protein family interactions
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Prostate cancer ( 23535732)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic venous disease ( 28374850) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Macular thickness ( 30535121) Peak expiratory flow ( 30804560) Small cell lung carcinoma ( 28604730) Systemic lupus erythematosus ( 28714469)
Interacting Genes		4 interacting genes: DUXAP9 NEDD4 NEDD4L SKAP2	19 interacting genes: APP BLK FAM102A FASLG FGR FRK FYB1 FYN HCK KHDRBS1 LCK LYN NCK2 PRAM1 PTK2B SRC SRMS TGFBR1 YES1
Entrez ID		6725	8935
HPRD ID		10250	05558
Ensembl ID		ENSG00000125508	ENSG00000005020
Uniprot IDs		Q9H3Y6	B7Z5R3 O75563
PDB IDs			3OMH
Enriched GO Terms of Interacting Partners?
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