SNAPC4 and POU2F1

Number of citations of the paper that reports this interaction (PubMedID 9418884)
35

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		SNAPC4	POU2F1
Description		small nuclear RNA activating complex polypeptide 4	POU class 2 homeobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm SnRNA-activating Protein Complex	Nuclear Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Intracellular Membrane-bounded Organelle RNA Polymerase II Transcription Factor Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription By RNA Polymerase III SnRNA Transcription SnRNA Transcription By RNA Polymerase II SnRNA Transcription By RNA Polymerase III	Cytokine-mediated Signaling Pathway Cell Differentiation SnRNA Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Interleukin-4 and Interleukin-13 signaling RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Crohn's disease ( 28067908 22936669 21102463) Glucose homeostasis traits ( 25524916) Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 28067908) Joint damage in rheumatoid arthritis ( 26498133) Metabolite levels ( 23823483) Ulcerative colitis ( 28067908 21297633)	Asthma ( 31619474) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Diastolic blood pressure ( 30224653) Liver enzyme levels ( 18940312) Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		8 interacting genes: BRF2 HNRNPD MAPK6 POU2F1 SNAPC1 SNAPC2 SNAPC5 TBP	49 interacting genes: APP AR BARD1 BRCA1 CEBPE CREB1 ESR1 FDXR HCFC1 HMGA1 HMGB2 HNF1A HOXB13 HOXC9 IRF9 LIFR MNAT1 MSX1 NCOR2 NFYA NPAT NR3C1 PARP1 PBX1 PGR PKNOX1 PLK3 POGZ POU2AF1 PRKACA PRKDC RARA RELA RXRA SNAPC4 SOX2 SP1 SP4 STAT5A STAT5B TBP THRA TLE4 TLE5 TLX2 TNF TXNRD1 VDR XRCC6
Entrez ID		6621	5451
HPRD ID		04146	01250
Ensembl ID		ENSG00000165684	ENSG00000143190
Uniprot IDs		A0A024R8F4 Q5SXM2	A0A024R8Y2 P14859
PDB IDs			1CQT 1E3O 1GT0 1HF0 1O4X 1OCT 1POG 1POU
Enriched GO Terms of Interacting Partners?
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