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SMARCE1 and SIN3A
Number of citations of the paper that reports this interaction (PubMedID
14559996
)
113
Data Source:
BioGRID
(pull down)
SMARCE1
SIN3A
Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
SIN3 transcription regulator family member A
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Chromosome
Nuclear Chromatin
Nucleus
Nucleoplasm
SWI/SNF Complex
Protein-containing Complex
NpBAF Complex
NBAF Complex
Histone Deacetylase Complex
Kinetochore
Chromatin
Cell
Nucleus
Nucleoplasm
Transcription Factor Complex
Nucleolus
Sin3 Complex
Transcriptional Repressor Complex
Molecular Function
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
Chromatin Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
N-acetyltransferase Activity
Nuclear Receptor Binding
Nucleosomal DNA Binding
Protein N-terminus Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
RNA Polymerase II Repressing Transcription Factor Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Transcription Corepressor Activity
RNA Binding
Histone Deacetylase Activity
Protein Binding
Protein Deacetylase Activity
Protein-containing Complex Binding
Biological Process
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Neurogenesis
ATP-dependent Chromatin Remodeling
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Transcription By RNA Polymerase II
In Utero Embryonic Development
Activation Of Innate Immune Response
Positive Regulation Of Defense Response To Virus By Host
Hematopoietic Progenitor Cell Differentiation
DNA Replication
Protein Deacetylation
Aging
Regulation Of Hormone Levels
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Histone Deacetylation
Regulation Of Lipid Metabolic Process
Cerebral Cortex Neuron Differentiation
Regulation Of Axon Extension
Positive Regulation Of Chromatin Silencing
Cellular Protein Localization
Negative Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Neuron Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Rhythmic Process
Response To Methylglyoxal
Cellular Response To Glucose Stimulus
Negative Regulation Of Protein Localization To Nucleus
Negative Regulation Of Histone H3-K27 Acetylation
Cellular Response To Dopamine
Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
SUMOylation of transcription cofactors
Regulation of lipid metabolism by PPARalpha
NoRC negatively regulates rRNA expression
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Loss of MECP2 binding ability to 5mC-DNA
Regulation of MECP2 expression and activity
MECP2 regulates neuronal receptors and channels
MECP2 regulates transcription of neuronal ligands
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Factors involved in megakaryocyte development and platelet production
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
29785011
)
Allergic rhinitis (
31361310
)
Asthma (
30929738
31619474
)
Asthma (childhood onset) (
30929738
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Eczema (
31361310
)
Estimated glomerular filtration rate (
31152163
)
Height (
20189936
)
Sudden cardiac arrest (
21658281
)
Interacting Genes
64 interacting genes:
AMOTL2
AR
ARID2
BAZ1B
BRAP
BRMS1
CCDC136
CCDC172
CDR2
CEP170P1
CEP63
CEP70
DISC1
EPS8
ESR1
ESR2
EXOC7
GATA1
GOLGA2
ING5
ITCH
JAKMIP2
KIFC3
KLF1
KRT15
KRT31
KRT40
KRTAP10-9
MDM2
MED4
MEOX2
MIPOL1
MRFAP1L1
MTUS2
NBPF22P
NCOA1
NCOA2
NCOA3
NOTCH2NLA
NR0B2
NR3C1
NUP62
PGR
PRMT5
RALBP1
RARB
RCOR1
RELB
RINT1
SIN3A
SIN3B
SMAD1
SMARCA4
SPAG5
SRC
STX11
SYCE1
TFE3
TFIP11
TNIK
TRIM54
TRIP10
TXLNA
USHBP1
91 interacting genes:
ARID4A
ARID4B
BCL11A
BCL6
BCL6B
BHLHE40
BRMS1
BRMS1L
CBFA2T2
COPS2
CTBP1
CTCF
CUL4B
CYTOR
DACH1
DDB1
DDX20
DHX30
ETV6
FOXK2
H3-4
HBP1
HCFC1
HDAC1
HDAC2
HDAC7
HDAC9
HEY2
HTT
IKZF1
IKZF4
ING1
IRF5
KLF10
KLF11
KLF13
KLF16
KLF9
LRCH4
MAD1L1
MBD2
MBD4
MECP2
MEN1
MNT
MORF4L2
MXD1
MXD4
MXI1
MYB
NCOR2
NFKB1
NFKB2
NR2E3
OGT
PA2G4
PHB
PHF12
PML
PRMT5
PTMA
RBBP4
RBBP7
RBP1
RBPJ
REL
RELA
RELB
RLIM
RUNX1T1
SAP18
SAP30
SETDB1
SFPQ
SKI
SMAD3
SMARCA4
SMARCC1
SMARCE1
SNW1
SPI1
STAT3
SYT1
TAL1
TFCP2
TGIF1
THAP11
TOPORS
TP53
TRIM28
ZBTB16
Entrez ID
6605
25942
HPRD ID
04382
09690
Ensembl ID
ENSG00000073584
ENSG00000169375
Uniprot IDs
A0A024R1S7
Q969G3
Q96ST3
PDB IDs
1PO4
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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