SMARCC2 and NOVA1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		SMARCC2	NOVA1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2	NOVA alternative splicing regulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Nucleoplasm Nucleolus Intracellular Membrane-bounded Organelle Synapse
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	MRNA Splicing, Via Spliceosome RNA Processing Chemical Synaptic Transmission Locomotory Behavior RNA Splicing Regulation Of RNA Metabolic Process Negative Regulation Of Cold-induced Thermogenesis
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Asthma ( 31619474)	BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28892062) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophilic esophagitis ( 25407941) Hand grip strength ( 29691431) Metabolite levels ( 23823483) Migraine ( 27182965) Neuritic plaque ( 31497858) Overweight status ( 25133637) Peanut allergy ( 29030101) Plasma anti-thyroid peroxidase levels ( 29678681) Zinc levels ( 26025379)
Interacting Genes		25 interacting genes: ARF6 ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TAF15 TERF1 TERF2IP	5 interacting genes: APP PCBP1 RPP14 SMARCC2 SRPK1
Entrez ID		6601	4857
HPRD ID		03437	03693
Ensembl ID		ENSG00000139613	ENSG00000139910
Uniprot IDs		A0A024RB22 F8VXC8 Q8TAQ2	B7Z770 P51513
PDB IDs			1DT4 2ANN 2ANR
Enriched GO Terms of Interacting Partners?
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