SMARCC2 and KLF1

Number of citations of the paper that reports this interaction (PubMedID 11018012)
80

Data Source:
BioGRID (pull down)

		SMARCC2	KLF1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2	Kruppel like factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Erythrocyte Differentiation Positive Regulation Of Transcription, DNA-templated Maternal Process Involved In Female Pregnancy Cellular Response To Peptide
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS		Asthma ( 31619474)	Clozapine-induced agranulocytosis ( 25187353) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		25 interacting genes: ARF6 ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TAF15 TERF1 TERF2IP	14 interacting genes: ARID1A CREBBP CSNK2A1 CSNK2A2 EP300 FLI1 HDAC1 PRKACA SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCE1
Entrez ID		6601	10661
HPRD ID		03437	07197
Ensembl ID		ENSG00000139613	ENSG00000105610
Uniprot IDs		A0A024RB22 F8VXC8 Q8TAQ2	Q13351
PDB IDs			2L2I 2MBH 2N23
Enriched GO Terms of Interacting Partners?
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