ACD and GAPDH

Number of citations of the paper that reports this interaction (PubMedID 21044950)
41

Data Source:
BioGRID (two hybrid)

		ACD	GAPDH
Description		ACD shelterin complex subunit and telomerase recruitment factor	glyceraldehyde-3-phosphate dehydrogenase
Image
GO Annotations	Cellular Component	Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Nucleoplasm Nuclear Body Shelterin Complex	Nucleus Cytoplasm Lipid Droplet Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome GAIT Complex Ribonucleoprotein Complex
	Molecular Function	Protein Binding Telomeric DNA Binding Protein-containing Complex Binding DNA Polymerase Binding	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Aspartic-type Endopeptidase Inhibitor Activity Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding Disordered Domain Specific Binding
	Biological Process	Telomere Maintenance Intracellular Protein Transport Telomere Capping Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region Establishment Of Protein Localization To Telomere	Microtubule Cytoskeleton Organization Gluconeogenesis Glycolytic Process Negative Regulation Of Endopeptidase Activity Regulation Of Macroautophagy Negative Regulation Of Translation Killing Of Cells Of Other Organism Peptidyl-cysteine S-trans-nitrosylation Positive Regulation Of Cytokine Secretion Protein Stabilization Defense Response To Fungus Neuron Apoptotic Process Killing By Host Of Symbiont Cells Positive Regulation By Organism Of Apoptotic Process In Other Organism Involved In Symbiotic Interaction Canonical Glycolysis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Interferon-gamma
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Telomere Extension By Telomerase DNA Damage/Telomere Stress Induced Senescence	Glycolysis Gluconeogenesis
Drugs			NADH Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-Aminoethyl)Benzenesulfonyl Fluoride Xanthinol Copper
Diseases
GWAS		Schizophrenia ( 25056061 29483656)	Blood protein levels ( 30072576)
Interacting Genes		60 interacting genes: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 ANXA8L1 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790	79 interacting genes: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DYNLL1 EGFR FBXO7 FKBP6 GADD45A GAS7 GOT2 GRIA2 GRM1 HES1 HNF4G HSPB2 HTT KARS1 KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 MAPK1 MTNR1A MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 PTPRF RAB2A RBM5 RPA2 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ
Entrez ID		65057	2597
HPRD ID		12417	00713
Ensembl ID		ENSG00000102977	ENSG00000111640
Uniprot IDs		A0A590TQL1 A0A5F9ZCY9 Q96AP0	P04406 V9HVZ4
PDB IDs		2I46 5H65 5I2X 5I2Y 5UN7 5XYF	1U8F 1ZNQ 2FEH 3GPD 4WNC 4WNI 6ADE 6IQ6
Enriched GO Terms of Interacting Partners?
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