ACD and LRRC25

Number of citations of the paper that reports this interaction (PubMedID 21044950)
41

Data Source:
BioGRID (two hybrid)

		ACD	LRRC25
Description		ACD shelterin complex subunit and telomerase recruitment factor	leucine rich repeat containing 25
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Nucleoplasm Nuclear Body Shelterin Complex	Cytoplasm Integral Component Of Membrane
	Molecular Function	Protein Binding Telomeric DNA Binding Protein-containing Complex Binding DNA Polymerase Binding	Protein Binding
	Biological Process	Telomere Maintenance Intracellular Protein Transport Telomere Capping Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region Establishment Of Protein Localization To Telomere
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Telomere Extension By Telomerase DNA Damage/Telomere Stress Induced Senescence
Drugs
Diseases
GWAS		Schizophrenia ( 25056061 29483656)	Hyperemesis gravidarum ( 29563502) Monocyte percentage of white cells ( 27863252) Severity of nausea and vomiting of pregnancy ( 29563502) Systemic lupus erythematosus ( 28714469)
Interacting Genes		60 interacting genes: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 ANXA8L1 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790	1 interacting genes: ACD
Entrez ID		65057	126364
HPRD ID		12417	09597
Ensembl ID		ENSG00000102977	ENSG00000175489
Uniprot IDs		A0A590TQL1 A0A5F9ZCY9 Q96AP0	Q8N386
PDB IDs		2I46 5H65 5I2X 5I2Y 5UN7 5XYF
Enriched GO Terms of Interacting Partners?
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