DEPTOR and TRIM41

Number of citations of the paper that reports this interaction (PubMedID 21516116)
94

Data Source:
BioGRID (two hybrid)

		DEPTOR	TRIM41
Description		DEP domain containing MTOR interacting protein	tripartite motif containing 41
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular	Nucleolus Cytoplasm Nuclear Body
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of TOR Signaling Intracellular Signal Transduction Negative Regulation Of Cell Size Regulation Of Extrinsic Apoptotic Signaling Pathway	Protein Ubiquitination Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Choroid plexus volume ( 31530798) Depressive and manic episodes in bipolar disorder ( 26297903) Depressive episodes in bipolar disorder ( 26297903) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549)
Interacting Genes		12 interacting genes: APP BTRC CCDC110 CHKA CUL5 FBXO25 LNX1 PSME3 RPS6KA1 RPS6KB1 TRAF1 TRIM41	62 interacting genes: AEN AKTIP APP BRAP CEP44 CHD2 CSNK2A2 DEPTOR EHHADH FAM124A FRA10AC1 GPATCH2L IKBKG KIFC3 KRTAP10-9 MAGEH1 MEOX2 MORF4L1 MPP3 NCK2 NEDD4L NOD2 PHC2 PHF7 PRKCA PRKCB PRPF31 PUS7L RNPS1 SORBS3 SRPK2 TLE5 TOP3B TRAIP TRIM17 TRIM26 TRIM4 TRIM52 UBE2D2 UBE2I ZBTB24 ZBTB38 ZBTB48 ZBTB8A ZFP2 ZFP64 ZNF138 ZNF24 ZNF250 ZNF26 ZNF263 ZNF264 ZNF266 ZNF329 ZNF417 ZNF473 ZNF490 ZNF564 ZNF587 ZNF670 ZSCAN21 ZSCAN26
Entrez ID		64798	90933
HPRD ID		13137	15558
Ensembl ID		ENSG00000155792	ENSG00000146063
Uniprot IDs		Q8TB45	Q8WV44
PDB IDs			2EGM
Enriched GO Terms of Interacting Partners?
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