TRIM41 and TOP3B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM41	TOP3B
Description		tripartite motif containing 41	DNA topoisomerase III beta
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Nuclear Body	Condensed Chromosome Nucleus
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding	DNA Binding RNA Binding DNA Topoisomerase Activity DNA Topoisomerase Type I Activity Protein Binding
	Biological Process	Protein Ubiquitination Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide	DNA Topological Change Chromosome Segregation
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Attention function in attention deficit hyperactive disorder ( 26174813) Bipolar disorder ( 31043756) Diastolic blood pressure ( 29208002) Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Interacting Genes		62 interacting genes: AEN AKTIP APP BRAP CEP44 CHD2 CSNK2A2 DEPTOR EHHADH FAM124A FRA10AC1 GPATCH2L IKBKG KIFC3 KRTAP10-9 MAGEH1 MEOX2 MORF4L1 MPP3 NCK2 NEDD4L NOD2 PHC2 PHF7 PRKCA PRKCB PRPF31 PUS7L RNPS1 SORBS3 SRPK2 TLE5 TOP3B TRAIP TRIM17 TRIM26 TRIM4 TRIM52 UBE2D2 UBE2I ZBTB24 ZBTB38 ZBTB48 ZBTB8A ZFP2 ZFP64 ZNF138 ZNF24 ZNF250 ZNF26 ZNF263 ZNF264 ZNF266 ZNF329 ZNF417 ZNF473 ZNF490 ZNF564 ZNF587 ZNF670 ZSCAN21 ZSCAN26	18 interacting genes: ADAMTSL4 C1QBP CENPF CHD8 CHIC2 FBLN5 GRN KRTAP4-12 MID2 PNMA2 RECQL5 SNRPB SPRED2 SSX2IP TRIM41 UPF2 ZFPM1 ZNF408
Entrez ID		90933	8940
HPRD ID		15558	04662
Ensembl ID		ENSG00000146063	ENSG00000100038
Uniprot IDs		Q8WV44	A0A024R1C2 A8K4N2 O95985
PDB IDs		2EGM	5GVC 5GVE
Enriched GO Terms of Interacting Partners?
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