BLVRB and ORM1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		BLVRB	ORM1
Description		biliverdin reductase B	orosomucoid 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Terminal Bouton Intracellular Membrane-bounded Organelle Extracellular Exosome	Extracellular Region Extracellular Space Platelet Alpha Granule Lumen Specific Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle Tertiary Granule Lumen
	Molecular Function	Biliverdin Reductase Activity Riboflavin Reductase (NADPH) Activity	Protein Binding
	Biological Process	Heme Catabolic Process Oxidation-reduction Process	Platelet Degranulation Regulation Of Immune System Process Acute-phase Response Inflammatory Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Neutrophil Degranulation Positive Regulation Of Interleukin-1 Secretion Positive Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of Tumor Necrosis Factor Secretion
Pathways		Heme degradation	Platelet degranulation Neutrophil degranulation
Drugs		Riboflavin NADH Biliverdine IX Alpha Riboflavin Monophosphate 2'-Monophosphoadenosine 5'-Diphosphoribose 7,8-dimethylalloxazine Mesobiliverdin Iv Alpha	Amsacrine Lidocaine Progesterone Chlorpromazine Oxycodone Dipyridamole Thalidomide
Diseases
GWAS		Otitis media ( 27632927) Otitis media (chronic) ( 27632927) Otitis media (recurrent) ( 27632927)	End-stage coagulation ( 23381943) Thrombin generation potential phenotypes ( 24357727) Tourette syndrome ( 22889924)
Interacting Genes		3 interacting genes: HMOX1 ORM1 RPL31	9 interacting genes: ALB BLVRB CCR5 GLUD1 GSDMB PIK3R3 SERPINE1 TMEM37 TP63
Entrez ID		645	5004
HPRD ID		02967	00724
Ensembl ID		ENSG00000090013	ENSG00000229314
Uniprot IDs		P30043 V9HWI1	P02763
PDB IDs		1HDO 1HE2 1HE3 1HE4 1HE5 5OOG 5OOH	3KQ0
Enriched GO Terms of Interacting Partners?
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