ARAP3 and ANKS1A

Number of citations of the paper that reports this interaction (PubMedID 17314030)
15

Data Source:
BioGRID (two hybrid)

		ARAP3	ANKS1A
Description		ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	ankyrin repeat and sterile alpha motif domain containing 1A
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GO Annotations	Cellular Component	Ruffle Cytosol Cytoskeleton Plasma Membrane Lamellipodium	Nucleoplasm Cytosol Neuron Projection
	Molecular Function	GTPase Activator Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Metal Ion Binding	Protein Binding Ephrin Receptor Binding
	Biological Process	Cytoskeleton Organization Signal Transduction Vesicle-mediated Transport Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Substrate-dependent Cell Migration Neuron Remodeling Ephrin Receptor Signaling Pathway Regulation Of Ephrin Receptor Signaling Pathway
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Cerebral amyloid deposition (PET imaging) ( 26252872) Diffuse large B cell lymphoma ( 25261932) Household income ( 31844048) Lung cancer ( 28604730) Mean arterial pressure ( 27618448) Offspring birth weight ( 31043758)	Coronary artery disease ( 24262325) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary heart disease ( 21378990) Height ( 28552196 23563607 18391951) Non-small cell lung cancer ( 23144319) Obesity-related traits ( 23251661) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for body mass index ( 25673412)
Interacting Genes		10 interacting genes: ANKS1A ARHGEF6 CD2AP CLNK GGA3 INPPL1 PARD6B SAMHD1 SH3KBP1 TNKS2	16 interacting genes: ADGRL1 ARAP3 ARHGAP10 DOK3 EGFR ERBB2 ERBB4 KLF15 NHLRC2 PIK3R3 RANBP3 RB1 SMARCD1 TRIT1 UBC YWHAG
Entrez ID		64411	23294
HPRD ID		09441	10610
Ensembl ID		ENSG00000120318	ENSG00000064999
Uniprot IDs		Q05CH1 Q8WWN8 Q9H7C1	Q05CP0 Q92625
PDB IDs		2KG5 2LNW 5JCP 5JD0	2LMR 2MYQ 6F7O
Enriched GO Terms of Interacting Partners?
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