SDC2 and REG3A

Number of citations of the paper that reports this interaction (PubMedID 8997243)
30

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		SDC2	REG3A
Description		syndecan 2	regenerating family member 3 alpha
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Golgi Lumen Plasma Membrane Cell Surface Integral Component Of Membrane Lysosomal Lumen Collagen-containing Extracellular Matrix	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Protein Binding PDZ Domain Binding Identical Protein Binding	Protein Binding Carbohydrate Binding Signaling Receptor Activity Identical Protein Binding Peptidoglycan Binding Oligosaccharide Binding
	Biological Process	Retinoid Metabolic Process Glycosaminoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Biological_process Cell Migration Post-translational Protein Modification Cellular Protein Metabolic Process Ephrin Receptor Signaling Pathway Dendrite Morphogenesis Regulation Of Dendrite Morphogenesis Leukocyte Migration	Acute-phase Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Cell Proliferation Positive Regulation Of Keratinocyte Proliferation Antimicrobial Humoral Response Response To Peptide Hormone Cell Wall Disruption In Other Organism Negative Regulation Of Keratinocyte Differentiation Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Wound Healing
Pathways		A tetrasaccharide linker sequence is required for GAG synthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Cell surface interactions at the vascular wall Syndecan interactions Syndecan interactions Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) EPHB-mediated forward signaling Defective B3GALT6 causes EDSP2 and SEMDJL1 Post-translational protein phosphorylation Retinoid metabolism and transport	Antimicrobial peptides
Drugs		Sargramostim
Diseases
GWAS		Post-traumatic stress disorder ( 26114229)	Body mass index ( 25673413)
Interacting Genes		27 interacting genes: ANOS1 BAG6 CASK CSF2 CYP2C18 EPHB2 EZR FGF2 FN1 HGF ITGB4 LAMA3 NF1 PF4 PPP3CC PRKCA PRKCB PRKCG REG3A SDCBP SERPINA1 SERPINC1 SPARC TGFB1 TGFBR3 TNFSF13 TRAPPC4	6 interacting genes: ANXA3 FN1 MDFI REG1A SDC2 TRHDE
Entrez ID		6383	5068
HPRD ID		00803	01342
Ensembl ID		ENSG00000169439	ENSG00000172016
Uniprot IDs		A0A024R9D1 E9PBI9 P34741	Q06141 Q53S56
PDB IDs		6ITH	1UV0 2GO0 4MTH
Enriched GO Terms of Interacting Partners?
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