BIK and S100A1

Number of citations of the paper that reports this interaction (PubMedID 27107012)
28

Data Source:
BioGRID (two hybrid)

		BIK	S100A1
Description		BCL2 interacting killer	S100 calcium binding protein A1
Image
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane	Extracellular Region Nucleus Sarcoplasmic Reticulum Z Disc M Band Protein-containing Complex Neuron Projection
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding
	Biological Process	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein Complex Assembly Positive Regulation Of Release Of Cytochrome C From Mitochondria	Negative Regulation Of Transcription By RNA Polymerase II Toll-like Receptor Signaling Pathway Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Sprouting Angiogenesis
Pathways			Regulation of TLR by endogenous ligand
Drugs			Olopatadine
Diseases
GWAS		Prostate cancer ( 25939597 21743057) Prostate cancer (SNP x SNP interaction) ( 22219177)
Interacting Genes		13 interacting genes: APP BCL2 BCL2A1 BCL2L1 BCL2L2 CREB3 CRKL FATE1 MCL1 NR2F2 S100A1 SOCS3 TANK	27 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BIK CACYBP CAPZA1 CEP20 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A4 S100B S100P SYN1
Entrez ID		638	6271
HPRD ID		04547	01489
Ensembl ID		ENSG00000100290	ENSG00000160678
Uniprot IDs		A0A024R4X6 Q13323	A0A0S2Z4H2 P23297
PDB IDs		2IPE	2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89
Enriched GO Terms of Interacting Partners?
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