BIK and BCL2A1

Number of citations of the paper that reports this interaction (PubMedID 10381646)
11

Data Source:
HPRD (in vivo)

		BIK	BCL2A1
Description		BCL2 interacting killer	BCL2 related protein A1
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GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Mitochondrial Membrane	Mitochondrial Outer Membrane
	Molecular Function	Protein Binding	Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity BH Domain Binding
	Biological Process	Apoptotic Process Male Gonad Development Apoptotic Mitochondrial Changes Positive Regulation Of Protein Complex Assembly Positive Regulation Of Release Of Cytochrome C From Mitochondria	Aging Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cerebral Cortex Development Negative Regulation Of Apoptotic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 25939597 21743057) Prostate cancer (SNP x SNP interaction) ( 22219177)	Eosinophil counts ( 29403010 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte count ( 29403010 27863252) Monocyte percentage of white cells ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Primary sclerosing cholangitis ( 27992413) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 29403010)
Interacting Genes		13 interacting genes: APP BCL2 BCL2A1 BCL2L1 BCL2L2 CREB3 CRKL FATE1 MCL1 NR2F2 S100A1 SOCS3 TANK	17 interacting genes: APP BAD BAK1 BAX BBC3 BCL2L11 BID BIK BMF BOK FAM9B GRB2 GSK3B HRK NR4A1 PMAIP1 SLC9A3R1
Entrez ID		638	597
HPRD ID		04547	03034
Ensembl ID		ENSG00000100290	ENSG00000140379
Uniprot IDs		A0A024R4X6 Q13323	Q16548
PDB IDs		2IPE	2VM6 3I1H 3MQP 4ZEQ 5UUK 5UUL 5UUP 5WHH 5WHI 6E3I 6E3J 6MBB 6MBC 6RJP
Enriched GO Terms of Interacting Partners?
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