CCL17 and VCAM1

Number of citations of the paper that reports this interaction (PubMedID 12193695)
15

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		CCL17	VCAM1
Description		C-C motif chemokine ligand 17	vascular cell adhesion molecule 1
Image
GO Annotations	Cellular Component	Extracellular Space	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Filopodium Apical Part Of Cell Extracellular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex
	Molecular Function	Signaling Receptor Binding Protein Binding Chemokine Activity CCR4 Chemokine Receptor Binding CCR Chemokine Receptor Binding	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding
	Biological Process	Monocyte Chemotaxis Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Multicellular Organism Development Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation Of Myoblast Differentiation Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Amine Metabolic Process Cytokine-mediated Signaling Pathway Membrane To Membrane Docking B Cell Differentiation Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of T Cell Proliferation Regulation Of Immune Response Leukocyte Tethering Or Rolling Oxidation-reduction Process Interferon-gamma-mediated Signaling Pathway Cell-cell Adhesion In Response To Extracellular Stimulus Cellular Response To Amyloid-beta
Pathways		Chemokine receptors bind chemokines	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling
Drugs			Ethanol Carvedilol Succinobucol
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269)	Multiple sclerosis ( 31604244 24076602 21833088) SjÃ¶gren's syndrome ( 24097067)
Interacting Genes		4 interacting genes: ACKR1 CCR4 CCR8 VCAM1	13 interacting genes: CCL17 CCL22 CTSG ELANE ETFA EXOSC2 EZR IL13 ITGAD ITGB1 ITGB7 MSN USP2
Entrez ID		6361	7412
HPRD ID		03309	01888
Ensembl ID		ENSG00000102970	ENSG00000162692
Uniprot IDs		Q92583	P19320
PDB IDs		1NR2 1NR4 5WK3	1IJ9 1VCA 1VSC
Enriched GO Terms of Interacting Partners?
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