CCL16 and CCR8

Number of citations of the paper that reports this interaction (PubMedID 10910894)
9

Data Source:
HPRD (in vivo, in vitro)

		CCL16	CCR8
Description		C-C motif chemokine ligand 16	C-C motif chemokine receptor 8
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cell Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Protein Binding Chemokine Activity Chemoattractant Activity CCR Chemokine Receptor Binding	Chemokine Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding
	Biological Process	Monocyte Chemotaxis Chemotaxis Inflammatory Response Cell Communication G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Positive Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Chemotaxis Immune Response Cell Adhesion G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Initial pursuit acceleration ( 29064472)	Daytime sleep phenotypes ( 27126917) Medication use (thyroid preparations) ( 31015401)
Interacting Genes		5 interacting genes: CCR1 CCR5 CCR8 HRH4 SDF2	6 interacting genes: CCL1 CCL16 CCL17 CCL4 TPST1 TPST2
Entrez ID		6360	1237
HPRD ID		03233	03497
Ensembl ID		ENSG00000275152	ENSG00000179934
Uniprot IDs		O15467	P51685
PDB IDs		5LTL
Enriched GO Terms of Interacting Partners?
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