ADRA1B and SAG

Number of citations of the paper that reports this interaction (PubMedID 8617782)
35

Data Source:
HPRD (in vivo)

		ADRA1B	SAG
Description		adrenoceptor alpha 1B	S-antigen visual arrestin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Caveola Nuclear Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytosol Membrane
	Molecular Function	Adrenergic Receptor Activity Alpha1-adrenergic Receptor Activity Protein Binding Protein Heterodimerization Activity	G Protein-coupled Receptor Binding Opsin Binding Protein Phosphatase Inhibitor Activity Phosphoprotein Binding
	Biological Process	Norepinephrine-epinephrine Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Behavior Intracellular Signal Transduction Glucose Homeostasis Positive Regulation Of MAPK Cascade Positive Regulation Of Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Regulation Of Cardiac Muscle Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway	G Protein-coupled Receptor Internalization Cell Surface Receptor Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Negative Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Adrenoceptors G alpha (q) signalling events G alpha (12/13) signalling events	Activation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Amphetamine Midodrine Ziprasidone Cabergoline Dapiprazole Amitriptyline Olanzapine Alfuzosin Clozapine Norepinephrine Mirtazapine Phenylephrine Loxapine Promazine Prazosin Imipramine Chlorpromazine Chlorpromazine Nortriptyline Amoxapine Clonidine Doxazosin Labetalol Nicardipine Verapamil Epinephrine Thioridazine Phentolamine Ergotamine Tamsulosin Methoxamine Trimipramine Risperidone Modafinil Propiomazine Fenoldopam Quinidine Phenoxybenzamine Maprotiline Oxymetazoline Ergoloid mesylate Carvedilol Doxepin Nefazodone Desipramine Terazosin Pergolide Bromocriptine Quetiapine Aripiprazole Lisdexamfetamine Paliperidone Mephentermine Methotrimeprazine Dextroamphetamine Phendimetrazine Propericiazine Acepromazine Thioproperazine Dronedarone R450 Epicept NP-1 Sertindole Mianserin Silodosin Droxidopa Xylometazoline Perospirone Brexpiprazole Dosulepin Etoperidone Cirazoline Synephrine Tiapride
Diseases			Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO) Retinitis pigmentosa (RP)
GWAS		Diastolic blood pressure ( 27841878) Plasma anti-thyroglobulin levels ( 29678681) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Calcium levels ( 20705733) Crohn's disease ( 22412388) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		11 interacting genes: ADRA1A AP2M1 EZR FLNC GNA11 GNAQ NOS1 PPP1R9B PRKCA SAG STAT1	4 interacting genes: ADRA1B CHRM2 EIF4E2 RHO
Entrez ID		147	6295
HPRD ID		00080	01625
Ensembl ID		ENSG00000170214	ENSG00000130561
Uniprot IDs		P35368	P10523
PDB IDs
Enriched GO Terms of Interacting Partners?
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