RPS4X and RPS7

Number of citations of the paper that reports this interaction (PubMedID 22939629)
262

Data Source:
BioGRID (biochemical, pull down, biochemical, biochemical)

		RPS4X	RPS7
Description		ribosomal protein S4 X-linked	ribosomal protein S7
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Ribosome Polysome Focal Adhesion Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit Cytoplasmic Ribonucleoprotein Granule Synapse Extracellular Exosome Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Centrosome Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Small-subunit Processome Protein-containing Complex Synapse Ribonucleoprotein Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding	RNA Binding MRNA 3'-UTR Binding Structural Constituent Of Ribosome Protein Binding Poly(U) RNA Binding Protein Kinase Binding MRNA 5'-UTR Binding Ubiquitin Ligase Inhibitor Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Multicellular Organism Development Positive Regulation Of Cell Proliferation Viral Transcription Positive Regulation Of Translation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Neural Tube Closure RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Positive Regulation Of Gene Expression Viral Transcription Cell Differentiation Ribosomal Small Subunit Biogenesis Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases			Diamond-Blackfan anemia (DBA)
GWAS			Lipid traits (pleiotropy) (HIPO component 1) ( 30289880)
Interacting Genes		10 interacting genes: ARPC3 CAMK2D CTBP2 HNRNPH3 MCM2 POR PTEN RPS15 RPS7 RPS8	9 interacting genes: CDKN2A IPO5 IPO7 NEK6 RPS4X STOML2 TNPO1 UPF2 ZBTB14
Entrez ID		6191	6201
HPRD ID		02427	04712
Ensembl ID		ENSG00000198034	ENSG00000171863
Uniprot IDs		B2R491 P62701	P62081
PDB IDs		4UG0 4V6X 5A2Q 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLI 6OM0 6OM7 6QZP	4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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