RPS7 and IPO7

Number of citations of the paper that reports this interaction (PubMedID 9687515)
166

Data Source:
HPRD (in vitro)

		RPS7	IPO7
Description		ribosomal protein S7	importin 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Centrosome Cytosol Ribosome Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit Small-subunit Processome Protein-containing Complex Synapse Ribonucleoprotein Complex	Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Membrane
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Structural Constituent Of Ribosome Protein Binding Poly(U) RNA Binding Protein Kinase Binding MRNA 5'-UTR Binding Ubiquitin Ligase Inhibitor Activity	Transporter Activity Protein Binding Ran GTPase Binding GTPase Regulator Activity Histone Binding SMAD Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Neural Tube Closure RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Positive Regulation Of Gene Expression Viral Transcription Cell Differentiation Ribosomal Small Subunit Biogenesis Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process	Protein Import Into Nucleus Signal Transduction Viral Process Innate Immune Response Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases		Diamond-Blackfan anemia (DBA)
GWAS		Lipid traits (pleiotropy) (HIPO component 1) ( 30289880)	Interleukin-10 levels ( 22205395)
Interacting Genes		9 interacting genes: CDKN2A IPO5 IPO7 NEK6 RPS4X STOML2 TNPO1 UPF2 ZBTB14	8 interacting genes: AKTIP H1-0 KPNB1 RAN RPL23A RPL5 RPS7 SRP19
Entrez ID		6201	10527
HPRD ID		04712	09280
Ensembl ID		ENSG00000171863	ENSG00000205339
Uniprot IDs		P62081	B3KNG9 O95373
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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