RPL12 and CBX1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RPL12	CBX1
Description		ribosomal protein L12	chromobox 1
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GO Annotations	Cellular Component	Nucleolus Cytosol Ribosome Focal Adhesion Postsynaptic Density Large Ribosomal Subunit Membrane Cytosolic Large Ribosomal Subunit Extracellular Exosome	Chromosome, Centromeric Region Nuclear Chromosome, Telomeric Region Chromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding Large Ribosomal Subunit RRNA Binding	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Ribosomal Large Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	HCMV Early Events
Drugs
Diseases
GWAS			Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)
Interacting Genes		6 interacting genes: APP CBX1 IPO11 PAXIP1 PTEN UBC	34 interacting genes: ABI3BP ARL5A BARD1 BRCA1 CBX3 CBX5 CHAF1A DCAF7 DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TBKBP1 TRIM24 TRIM28 UCHL1 VHL VTN
Entrez ID		6136	10951
HPRD ID		01603	05149
Ensembl ID		ENSG00000197958	ENSG00000108468
Uniprot IDs		P30050	P83916 Q6IBN6
PDB IDs		4V6X 5A8L 5AJ0 6OLG	2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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