CBX1 and ABI3BP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CBX1	ABI3BP
Description		chromobox 1	ABI family member 3 binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nuclear Chromosome, Telomeric Region Chromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage	Extracellular Region Interstitial Matrix Extracellular Space Collagen-containing Extracellular Matrix
	Molecular Function	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding	Extracellular Matrix Structural Constituent Collagen Binding Heparin Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways		HCMV Early Events
Drugs
Diseases
GWAS		Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)	Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Alcohol dependence ( 26365420) Asthma (childhood onset) ( 23829686) Carotid plaque burden ( 28282560) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Joint mobility (Beighton score) ( 27182965) Multiple sclerosis ( 31604244) Optic disc area ( 25631615 28073927) Optic disc size ( 31809533) Post bronchodilator FEV1 in COPD ( 26634245) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		34 interacting genes: ABI3BP ARL5A BARD1 BRCA1 CBX3 CBX5 CHAF1A DCAF7 DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TBKBP1 TRIM24 TRIM28 UCHL1 VHL VTN	6 interacting genes: ABI3 CBX1 FZD5 GOT1 GRB2 MBNL1
Entrez ID		10951	25890
HPRD ID		05149	09380
Ensembl ID		ENSG00000108468	ENSG00000154175
Uniprot IDs		P83916 Q6IBN6	D3YTG3 Q7Z7G0
PDB IDs		2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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