RELB and BCL7A

Number of citations of the paper that reports this interaction (PubMedID 14743216)
300

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		RELB	BCL7A
Description		RELB proto-oncogene, NF-kB subunit	BAF chromatin remodeling complex subunit BCL7A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Centrosome Cytosol Transcriptional Repressor Complex Protein-containing Complex I-kappaB/NF-kappaB Complex	Cellular_component
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Kinase Binding Identical Protein Binding	Molecular_function Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Stimulatory C-type Lectin Receptor Signaling Pathway Inflammatory Response I-kappaB Kinase/NF-kappaB Signaling Antigen Processing And Presentation Lymphocyte Differentiation Negative Regulation Of Interferon-beta Production Circadian Regulation Of Gene Expression Cellular Response To Stress Response To Cytokine NIK/NF-kappaB Signaling Myeloid Dendritic Cell Differentiation T-helper 1 Cell Differentiation Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Osmotic Stress	Negative Regulation Of Transcription, DNA-templated
Pathways		Dectin-1 mediated noncanonical NF-kB signaling CD209 (DC-SIGN) signaling NIK - noncanonical NF-kB signaling
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Carotid intima media thickness (maximum) ( 31801372) Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Cerebrospinal fluid AB1-42 levels ( 29274321) Cerebrospinal fluid p-tau levels ( 29274321) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid t-tau levels ( 29274321) Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321) Hippocampal volume ( 29274321) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Logical memory (delayed recall) ( 29274321) Logical memory (immediate recall) ( 29274321)	Height ( 25282103) Mean corpuscular volume ( 27863252) Mean platelet volume ( 24026423) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		25 interacting genes: BCL7A BUD31 CDK1 CTSL DPF2 EHMT2 EZH2 GSK3B HDAC6 KPNA2 KPNA6 MALT1 MT1M MTAP NFKB1 NFKB2 RELA SIN3A SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCE1 UQCRFS1 USP11	3 interacting genes: ALAS1 CD151 RELB
Entrez ID		5971	605
HPRD ID		06886	03243
Ensembl ID		ENSG00000104856	ENSG00000110987
Uniprot IDs		D6R992 Q01201	Q4VC05
PDB IDs
Enriched GO Terms of Interacting Partners?
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